Skin and Wound Healing

Question 1

To functions of the skin belong:

a) metabolism
b) protection
c) sensation
d) thermoregulation

Answer 1

a) metabolism
b) protection
c) sensation
d) thermoregulation

Question 2

Which of the following statements about epidermis are right:

a) in developmental respect, it is of endodermal origin;
b) its stem cells are represented by the basal layer;
c) it harbors pigment cells that produce melatonin;
d) consisting of up to five distinct cell layers it represents an atypical epithelium.

Answer 2

b) its stem cells are represented by the basal layer;

d) consisting of up to five distinct cell layers it represents an atypical epithelium.

Question 3

Bring into right order from proximal to distal:

a) Stratum granulosum
b) Stratum corneum
c) Stratum basale
d) Stratum spinosum
e) Stratum lucidum

Answer 3

1. Stratum basale
2. Stratum spinosum
3. Stratum granulosum
4. Stratum lucidum
5. Stratum corneum

Question 4

Which epidermal cell type is derived from the neural crest:

a) keratinocyte
b) epidermal dendritic cell
c) melanocyte
d) None of the above.

Answer 4

c) melanocyte

Question 5

Which sensory cells of the dermis detect what kind of stimulus:

Ruffini corpuscles

Tactile discs

Root hair plexus

Free nerve endings

Answer 5

Ruffini corpuscles - pressure

Tactile discs - light touch

Root hair plexus - movement of hairs

Free nerve endings - pain

Question 6

The cornification of the epithelial surface layers is a result of the accumulation of the protein:

a) Keratin inside the cells
b) Keratin between the cells
c) Melanin inside the cells
d) Melanin between the cells

Answer 6

a) Keratin inside the cells

Question 7

The two main layers of tissue forming the skin are:

a) dermis and hypodermis
b) epidermis and dermis
c) epidermis and mesodermis
d) epidermis and hypodermis

Answer 7

b) epidermis and dermis

Question 8

The main extra-cellular-matrix component of the dermis is:

a) proteoglycan
b) murren
c) melanin
d) collagen

Answer 8

d) collagen

Question 9

For proper wound closure it is necessary that:
a) fibrinogen forms from fibrin

b) blood platelets bind to proteins of extracellular matrix in wound
c) thrombin is secreted from liver
d) fibrinogen gets proteolytically modified to allow for polymerization

Answer 9

b) blood platelets bind to proteins of extracellular matrix in wound
c) thrombin is secreted from liver
d) fibrinogen gets proteolytically modified to allow for polymerization

Question 10

To the three major steps of wound healing belong:

a) remodeling
b) retention
c) inflammation
d) clotting

Answer 10

a) remodeling

c) inflammation

Question 11

Which list represents the right temporal order of events happening during wound healing:

a) re-epitheliazation – blood clotting – re-vascularization – collagen deposition
b) blood clotting – eschar formation – re-epitheliazation – collagen deposition
c) neutrophil invasion – eschar formation – re-epitheliazation – scar formation
d) eschar formation – inflammation – new tissue formation - remodeling

Answer 11

b) blood clotting – eschar formation – re-epitheliazation – collagen deposition
c) neutrophil invasion – eschar formation – re-epitheliazation – scar formation