Skin and Soft Tissue Infections Flashcards

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1
Q

Skin anatomy (inside –> outside)

A

subcutaneous tissue
dermis
epidermis

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2
Q

Skin (function/protective mechanisms)

A
  • serves as a barrier
  • contains keratin (water-resistant)
  • high salt and acidic pH
  • normal flora: S. epi, CoNS, Propionibacterium, Corynebacterium, yeasts
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3
Q

Infections of the epidermis and dermis

A
  • infection in/around hair follicles: folliculitis, furuncolosis, carbuncles
  • infection of keratinized layer: dermatophyte fungi, Trichophyton, Epidermophyton, Microsporum
  • infection of deeper layers: due to traumatic breaks in skin (erythrasma, hidradentis suppurativa, pilonidal cysts, sebaceous cysts)
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4
Q

Folliculitis, furuncolosis, carbuncles (causes)

A
  • S. aureus is most common
  • Enterobacteriaceae
  • Pseudomonas aeruginosa associated with hot tubs
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5
Q

Trichophyton, Epidermophyton, Microsporum

A
  • ringworm
  • tinea pedis: athlete’s foot
  • tinea versicolor: Malassezia furfur
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6
Q

Erythrasma

A
  • chronic infection of keratinized layer

- Corynebacterium, Mycobacterium marinum

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7
Q

Hidradentis suppurativa

A
  • obstructed apocrine gland (sweat gland)

- S. aureus, anaerobic strep, Bacteroides

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8
Q

pilonidal cysts

A

B. fragilis

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9
Q

Sebaceous cysts

A

Anaerobic cocci, bacteroides, propionibacterium, staphylococci, streptococci

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10
Q

Subcutaneous tissue infections

A
  • abscesses, ulcers, boils: S. aureus, polymicrobial

- Erisipelas: cellulitis and streptococcal necrotizing fasciitis

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11
Q

Cellulitis

A
  • usually in extremities, usually staph or strep
  • anaerobic and aerobic mixed
  • E. coli, Enterics, S. aureus, Strep, Anaerobes
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12
Q

Necrotizing fasciitis

A
  • Group A Strep, S. aureus, Bacteroides, Clostridium

- Gas gangrene: C. perfringens

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13
Q

Infections of Muscle Fascia and Muscles

A
  • Necrotizing fascitis
  • Progressive bacterial synergistic gangrene (post-op infection, polymicrobial)
  • Myositis
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14
Q

Myositis

A
  • extensive muscle involvement
  • S. aureus, Clostridium, Group A and B strep
  • Virbio vulnificus, Aeromonas, other wound-associated bacteria
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15
Q

Wound Infections

A
  • post-operative infections (normal flora or nosocomial organisms, S. aureus)
  • human bite wounds (mouth flora, strep, S. aureus, Eikenella, Anaerobes)
  • animal bite wounds (pasteurella, strep, staph, anaerobes)
  • burns (Pseudomonas, S. aureus, Enterobacter, E. coli)
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16
Q

Organisms related to poor blood supply

A

S. aureus, S. pyogenes, Anaerobes

17
Q

Organisms related to open ulcers

A

P. aeruginosa, Enterobacteriaceae, bowel flora in decubitus ulcers

18
Q

Organisms related to draining sinuses/fistulas with bone involvement

A

S. aureus, Enterobacteriaceae, P. aeruginosa, anaerobes

19
Q

Organisms related to Actinomycosis with or without bone involvement

A

Actinomyces, Propionibacterium, Prevotella, non-spore-forming anaerobes

20
Q

Organisms related to breast abscesses

A

non-spore-forming anaerobes

21
Q

Other organisms related to chronic draining sinuses/fistulas

A

Nocardia infections (brasiliensis)

22
Q

Fistula infections

A

due to contamination with normal flora

23
Q

Vesicles/Bullae

A
  • fluid-filled lesion
  • gram-stain
  • S. aureus, Group A strep, P. aeruginosa, Vibrio vulnificus
  • needle aspiration for fluid
24
Q

Lymphadenitis

A

M. scrofulaceum, Group A strep, S. aureus, Y. pestis

25
Q

Skin infections with bacteremia

A
  • Petechiae with meningococcemia
  • Cutaneous ulcers and Vibrio vulnificus sepsis
  • S. aureus, P. aeruginosa, M. leprae, T. pallidum, Rickettsia, Systemic mycoses
26
Q

Specimens to collect

A
  • aspirates and exudates are best
27
Q

Lab ID

A
  • Direct smear: gram stain (or acid-fast if Myco)
  • culture on plates (SBA, MAC, Choc, etc.)
  • culture of viruses (look for cytopathic effect)