Genital Pathogens and STI's Flashcards
Sexually transmitted infections (STI’s)
- spread via person-to-person sexual contact
- some can be transmitted mother to baby during birth or blood products
CDC reccomendations
- yearly chlamydia and gonorrhea screenings for at risk women
- annual chlamydia screening for women age 25
- annual screening of men who have sex with men for syphilis, gonorrhea, chlamydia, and HIV
Normal urethral flora
CoNS, Corynebacteria, Anaerobes, Lactobacillus, non-hemolytic strep, Neisseria
Normal vulva and foreskin flora
Mycobacterium smegmatis, Gram-positive organisms
Prepubescent and postmenopausal female genital flora
- CoNS, Corynebacteria
- varies with pH and estrogen
Normal genital flora of reproductive age females
Enterobacteriaceae, Strep, Staph, Anaerobes (Lactobacillus), Clostridium, transient yeast
Endogenous Genital infections
result from organisms that are normal flora
Exogenous Genital infections
STI’s, result from instrumentation or foreign bodies
Primary Genital Pathogens
- Chlamydia trachomatis
- Neisseria gonorrhoeae
- Treponema pallidum
- Human papilloma virus
- Gardnerella vaginalis: bacterial vaginosis, premature labor
- Trichomonas vaginalis
- Haemophilus ducreyi
- Klebseilla granulomatis
- Mycoplasma hominis
- Ureaplasma urealyticum
- cervicitis with mucus
- PID leading to infertility
- Preterm births
Chlamydia trachomatis
- may be #1 STI
- penile malignancy, cervical carcinoma
- genital warts
Human papilloma virus (HPV)
Gardnerella vaginalis
bacterial vaginosis, premature labor, low birth rates
Trachomonas vaginalis
vaginitis
- questionable role in genital infection
- PID, pyelonephritis
- postpartum fever with morbidity and still births
Mycoplasma hominis
- acute non-gonococcal urethritis
- acute urethral syndrome in females with reproductive failure
Ureaplasma urealyticum
Organisms associated with homosexual practice
- Protozoa: Giardia, Entamoeba
- Bacteria: Salmonella, Shigella, Campylobacter, N. meningitidis
- Viruses: CMV, Hepatitis, HIV
Genital tract pathogens
- Fungi: Candida, yeast
- Viruses: CMV, HPV, Herpes
- Protozoa: Trichomonas vaginalis, scabies, lice
Genital tract infections (clinical manifestations)
- women asymptomatic
- discharge, dysuria, skin lesions
Vaginosis and Vaginitis
- inflammation of vaginal mucosa
- discharge and odor
- Trichomonas vaginalis and Candida albicans
Bacterial vaginosis
- polymicrobial or Gardnerella vaginalis
- most common vaginal infection in women of child-bearing age