Skin and Function 3

Question 1

What is the dermo-epidermal junction?

Answer 1

Interface between dermis and epidermis

Question 2

What is the dermo-epidermal junction’s role in epithelial mesenchymal interactions?

Answer 2

• Support, anchorage, adhesion, growth and differentiation of basal cells
• Semi-permeable membrane acting as barrier and filter

Question 3

What type of patient gets epidermolysis Bullosa?

Answer 3

Babies

Question 4

What disease occurs if you don’t have the dermo-epidermal junction?

Answer 4

Epidermolysis Bullosa

Question 5

What are the main cells in dermis?

Answer 5

Mainly fibroblasts

Question 6

What is in the dermis?

Answer 6

Ground substance
Cells- fibroblasts, macrophages, mast cells, lymphocytes, langerhans
Fibres- collagen/elastin
Muscles, blood vessels, lymphatics and nerves

Question 7

Types of cells in dermis?

Answer 7

Fibroblasts 
Macrophages 
Mast cells 
Lymphocytes 
Langerhans

Question 8

In urticaria what happens?

Answer 8

Mast cells pop and release histamines (this is why you take anti-histamines in allergies)

Question 9

What gives your skin strength?

Answer 9

Collagen

Question 10

If you lose elastic fibres in your skin because of long term UV exposure what happens?

Answer 10

Wrinkles

Question 11

Flow of blood?

Answer 11

Arteriole– precapillary sphincters–arterial–venous capillaries–post capillary venules–collecting venules

Question 12

What are lymphatics?

Answer 12

Sub-epidermal meshed networks

Question 13

What do lymphatic vessels do?

Answer 13

Continual drainage of plasma proteins, extravasated cells and XS interstitial fluid

Question 14

Important immune functions of lymphatic vessels?

Answer 14

• Immune surveillance by circulating lymphocytes and Langerhan cells
• Channeling of micro-organisms/ toxins

Question 15

Name of somatic sensory nerves?

Answer 15

Dematomes

Question 16

Autonomic nerve supply?

Answer 16

Blood vessels, nerves and glands

Question 17

Special pressure receptors?

Answer 17

Pacinian corpuscle

Question 18

Special vibration receptors?

Answer 18

Meissners corpuscles

Question 19

Hair follicles term?

Answer 19

Pilosebaceous unit

Question 20

Every hair unit has?

Answer 20

A sebaceous gland

Question 21

Hair that you can’t pull out?

Answer 21

Anagen

Question 22

Describe involuting/catagen hair?

Answer 22

Hair that has stopped growing but isn’t shedding

Question 23

Types of skin glands?

Answer 23

Sebaceous
Apocrine
Eccrine

Question 24

Describe sebaceous gland secretion?

Answer 24

Holocrine opening into pilary canal

Question 25

What are the largest glands in the face and chest?

Answer 25

Sebaceous glands

Question 26

Functions of sebaceous glands?

Answer 26

Control moisture loss

Protect from fungal infection

Question 27

Where do apocrine sweat glands develop?

Answer 27

Part of pilosebaceous unit

Question 28

Where are apocrine sweat glands?

Answer 28

Axillae and perineum

Question 29

Apocrine swet glands are——- dependant?

Answer 29

Androgen

Question 30

What do apocrine sweat glands produce?

Answer 30

Oily fluid.

Question 31

Where are eccrine sweat glands?

Answer 31

Whole skin surface

-palms, soles and axillae particularly

Question 32

Nerve supply of eccrine sweat glands?

Answer 32

Sympathetic cholinergic supply

-mental, thermal and gustatory stimulation

Question 33

Functions of eccrine sweat glands?

Answer 33

• Cooling by evaporation

- Moisten palms/soles to aid grip

Question 34

Function of apocrine sweat glands?

Answer 34

Unknown

Question 35

What are sebaceous glands sensitive to?

Answer 35

Hormones