Skin Flashcards

1
Q

Appropriate melanoma margins;

A

in situ–> 0.5- 1 cm

0.1–1 mm –> 1 cm

1-2 mm –> 1 or 2 cm

> 2 mm–> 2 cm

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2
Q

Subungal melanoma treatment?

A

not as aggressive as once thought

no need for amputation, wide local excision ok

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3
Q

What is dermatofibroma protuberans?

A

rare, soft tissue tumor

excellent survival rate

rarely mets

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4
Q

Dermatofibroma protuberans stain for what marker?

A

CD34

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5
Q

What margins do you need for dermatofibroma protuberans?

A

2 cm

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6
Q

Why do you need 2 cm margins for dermatofibroma protuberans?

A

tend to recur

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7
Q

Sentinel LN biopsy for dermatofibroma protuberans?

A

NO

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8
Q

Radiotherapy for dermatofibroma protuberans?

A

very responsive to it

especially when they recur

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9
Q

For locally advanced or metastatic dermatofibroma protuberans, what medicine can we use?

A

imatinib

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10
Q

What tysoine kinase inhibitor can we use on dermatofibroma protuberans?

A

imatinib

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11
Q

What’s merkel cell carcinoma?

A

aggressive neuroendocrine cutaneous tumor

arise from merkel cells on the skin

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12
Q

Merkel cell tumors are linked to?

A

immunosuppresion

polyomavirus

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13
Q

Radiation therapy for merkel cell carcinoma?

A

adjuvant radiation therapy after removal is standard of care

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14
Q

Tx for merkel cell carcinoma?

A

wide local excision

post-removal radiation therapy

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15
Q

These extend beyond borders of a wound;

A

keloids

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16
Q

When do we performa SLND bx for melanoma?

A

recommended for all pts with melanoma thickness >1 mm

pts with 0.75- 1 mm thickness with worrying signs like ulceration, increased mitoses, positive deep margin, young pt

17
Q

Herpetic whitlow caused by?

A

HSV-1/2 of the finger

18
Q

Scaled skin syndrome results from?

A

staphylococcal, exotoxin induced detachment of the epidermal layer

19
Q

Chronic inflammatory dx affecting the apocrine gland bearing areas of axilla, groin, inguinal regions;

A

hidradenitis

20
Q

What’s Cloquet’s node?

A

node within femoral canal

bridging node between superficial and deep nodal basins

21
Q

Whats actinic keratoses?

A

red crusty lesions that often weep

precursor lesions for squamous cell carcinoma of skin

22
Q

Precursor lesion of squamous cell carcinoma of skin>?

A

actinic keratoses

23
Q

Single lesion of actinic keratoses how is it treated?

A

cryotherapy

24
Q

Regular treatment for actinic keratoses?

A

ablative, cryotherapy, chemical

25
Q

Treatment of choice for actinic keratoses?

A

cryotherapy

26
Q

Chronic wounds often arrested at what stage of wound healing?

A

inflammatory

usually wound healing is arrested due to bacteria, necrosis, hypoxia

27
Q

MC skin cancer spread to duodenum?

A

melanoma

28
Q

Predominant cell in a healing wound in 24-48 hrs?

A

neutrophils

29
Q

when do we see macrophages in wound healing?

A

48-96 hrs