Skin Flashcards
Appropriate melanoma margins;
in situ–> 0.5- 1 cm
0.1–1 mm –> 1 cm
1-2 mm –> 1 or 2 cm
> 2 mm–> 2 cm
Subungal melanoma treatment?
not as aggressive as once thought
no need for amputation, wide local excision ok
What is dermatofibroma protuberans?
rare, soft tissue tumor
excellent survival rate
rarely mets
Dermatofibroma protuberans stain for what marker?
CD34
What margins do you need for dermatofibroma protuberans?
2 cm
Why do you need 2 cm margins for dermatofibroma protuberans?
tend to recur
Sentinel LN biopsy for dermatofibroma protuberans?
NO
Radiotherapy for dermatofibroma protuberans?
very responsive to it
especially when they recur
For locally advanced or metastatic dermatofibroma protuberans, what medicine can we use?
imatinib
What tysoine kinase inhibitor can we use on dermatofibroma protuberans?
imatinib
What’s merkel cell carcinoma?
aggressive neuroendocrine cutaneous tumor
arise from merkel cells on the skin
Merkel cell tumors are linked to?
immunosuppresion
polyomavirus
Radiation therapy for merkel cell carcinoma?
adjuvant radiation therapy after removal is standard of care
Tx for merkel cell carcinoma?
wide local excision
post-removal radiation therapy
These extend beyond borders of a wound;
keloids