Skin Flashcards
Appropriate melanoma margins;
in situ–> 0.5- 1 cm
0.1–1 mm –> 1 cm
1-2 mm –> 1 or 2 cm
> 2 mm–> 2 cm
Subungal melanoma treatment?
not as aggressive as once thought
no need for amputation, wide local excision ok
What is dermatofibroma protuberans?
rare, soft tissue tumor
excellent survival rate
rarely mets
Dermatofibroma protuberans stain for what marker?
CD34
What margins do you need for dermatofibroma protuberans?
2 cm
Why do you need 2 cm margins for dermatofibroma protuberans?
tend to recur
Sentinel LN biopsy for dermatofibroma protuberans?
NO
Radiotherapy for dermatofibroma protuberans?
very responsive to it
especially when they recur
For locally advanced or metastatic dermatofibroma protuberans, what medicine can we use?
imatinib
What tysoine kinase inhibitor can we use on dermatofibroma protuberans?
imatinib
What’s merkel cell carcinoma?
aggressive neuroendocrine cutaneous tumor
arise from merkel cells on the skin
Merkel cell tumors are linked to?
immunosuppresion
polyomavirus
Radiation therapy for merkel cell carcinoma?
adjuvant radiation therapy after removal is standard of care
Tx for merkel cell carcinoma?
wide local excision
post-removal radiation therapy
These extend beyond borders of a wound;
keloids
When do we performa SLND bx for melanoma?
recommended for all pts with melanoma thickness >1 mm
pts with 0.75- 1 mm thickness with worrying signs like ulceration, increased mitoses, positive deep margin, young pt
Herpetic whitlow caused by?
HSV-1/2 of the finger
Scaled skin syndrome results from?
staphylococcal, exotoxin induced detachment of the epidermal layer
Chronic inflammatory dx affecting the apocrine gland bearing areas of axilla, groin, inguinal regions;
hidradenitis
What’s Cloquet’s node?
node within femoral canal
bridging node between superficial and deep nodal basins
Whats actinic keratoses?
red crusty lesions that often weep
precursor lesions for squamous cell carcinoma of skin
Precursor lesion of squamous cell carcinoma of skin>?
actinic keratoses
Single lesion of actinic keratoses how is it treated?
cryotherapy
Regular treatment for actinic keratoses?
ablative, cryotherapy, chemical
Treatment of choice for actinic keratoses?
cryotherapy
Chronic wounds often arrested at what stage of wound healing?
inflammatory
usually wound healing is arrested due to bacteria, necrosis, hypoxia
MC skin cancer spread to duodenum?
melanoma
Predominant cell in a healing wound in 24-48 hrs?
neutrophils
when do we see macrophages in wound healing?
48-96 hrs
