Anesthesia

Question 1

Pancuronium contraindicted in CAD because?

Answer 1

causes tachycardia

Question 2

Main adverse effect of pancuronium is?

Answer 2

tachycardia

Question 3

How long does pancuronium last?

Answer 3

up to 90 mins

Question 4

This anesthesia drug causes adrenal suppression;

Answer 4

etomidate

Question 5

Atracurium is an intermediate acting drug and its main side effect is?

Answer 5

release of histamine

Question 6

This drug causes rhabdomyolsysis, malignant hyperthermia, muscle aches:

Answer 6

succynilcholine

Question 7

Most common anesthetic complication post-op requiring hospital admission from ambulatory surgery?

Answer 7

post-op nausea/vomiting

Question 8

Principal collagen is healed wounds/scars?

Answer 8

type I

Question 9

What two proteins make up collagen synthesis?

Answer 9

hydroxyproline

hydroxylysine

cross-linked by vit c

Question 10

Type II collagen mostly found in ?

Answer 10

cartilage

Question 11

Type III collagen found in?

Answer 11

blood vessels
uterus
fetal skin

Question 12

Type IV collagen found?

Answer 12

basement membrane

Question 13

Most common type of collagen in the body?

Answer 13

type I

found in old healed scars/wounds

Question 14

Malignant hyperthermia caused by what mutation?

Answer 14

mutation in ryanidine receptor gene located in sarcoplasmic reticulum in skeletal muscle
(this causes drastic increase in intracellular Ca levels)

inherited AD

Question 15

Tx for malignant hyperthermia?

Answer 15

dantrolene

Question 16

How does vasopressin work?

Answer 16

causes peripheral vasoconstriction via V1 receptor stimulation

used as a second line agent in vasodilatory shock

Question 17

What is a side effect of protamine sulfate reversal after heparin administration?

Answer 17

hypotension

mediated by degranulation of mast cells and release of NO

Question 18

Most reliable indicator that pt is intubated in the trachea and not the esophagus is?

Answer 18

End-tidal Co2

Question 19

Whats the MOA of dobutamine ?

Answer 19

acts on B1 receptors in the heart

b1 agonist to increase cardiac contractility

at higher doses exerts b2 agonist activity which causes vasodilation of periphery

Question 20

Side effect of mycophenil mofetil?

Answer 20

leukopenia, diarrha

immunosuppressive medication

Question 21

Side effect of cyclosporine?

Answer 21

renal toxicity , neurotoxicity

Question 22

Side effect of azathioprine?

Answer 22

bone marrow suppression

Question 23

Side effect of tacrolimus?

Answer 23

renal toxicity, neurotoxicity

Question 24

Side effect of sirolimus/everolimus?

Answer 24

hyper triglyceridemia