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Science for Medicine > Skin > Flashcards

Skin Flashcards

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Biology 101 flashcards
1
Q

Epidermis

A

Prevent Water Loss by Evaporation
Stratified Squamous Keratinising Epithelium Tissue
Boundary bw external and internal compartments
Consists of Strata Layers
Waterproof
Intercellular Spaces filled with lipid

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2
Q

Dermis

A

Permits Body Cooling
Connective Tissue
Gives Structural Strenght

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3
Q

Hypodermis

A

Anchors skin to underlying structures

Not part of skin

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4
Q

Stratum Basale (germinativum)

A

Tall columnar cells interspersed with melanocytes and Merkel Cells
Cells bound to BM (BL+RL) by hemidesmosomes
Dermal Papillae - Irregular Interface with dermis
Stem Cells (undifferentiated)

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5
Q

Dermal Papillae

A

Stratum Basale Irregular Interface with Dermis

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6
Q

Stratum Spinosum

A

Desmosome cell-cell Junctions
Preparative Layer for Keratinisation
Langerhan Cells
Keratinocytes

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7
Q

Stratum Granulosum

A

Presence of Granule

Granules of Keratohyaline (keratin precursor)

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8
Q

Stratum Lucidum, Corneum (no organelles)

A

Keratohyaline - Keratin conversion

Disulphide Linkages - strength

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9
Q

Keratinisation

A 
Keratin is deposited in cells and these become horny as in dead skin, nails, hair.
Stratum basale - stem cell division
Incorporation of Keratin 
Cell Flattening
Loss of nuclei and proliferation
Stratum corneum - dead cells
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10
Q

Psoriasis

A

Autoimmune disorder affecting keratinisation

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11
Q

Dermis

A

Papillary Layer

Reticular Layer

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12
Q

Papillary Layer

A

Loose Connective Tissue
Cellular: Macrophages
Blood Vessels - Thermoregulation, Nutrition
Nerve Endings - Sense Organ

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13
Q

Reticular Layer

A

Dense irregular connective tissue
Fibrous - Collagen bundles in 3planes
Elastic Fibres

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14
Q

Melanocytes

A

In stratum Basale - Germinativum

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15
Q

Nail Bed (Hyponychium)

A

Specialised form of skin Epithelium

Like Stratum Corneum

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16
Q

Skin Glands

A

Sebaceous - sebum
Apocrine Sweat Glands - axilla, protein rich
Eccrine - sweat

17
Q

Eccrine Sweat Glands

A 
Simple tubular glands
In dermis
Coiled in dermis 
Spiral in epidermis
Watery secretion
Thermoregulation
18
Q

Skin Repair

A

Blood Clot
Scrab
Granulation Tissue
Scar

Science for Medicine (9 decks)

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