skin 12: summary Flashcards
Need to know ALL names for agent/disease!
Variola virus – smallpox:
VZV - chickenpox and zoster
Human Parvovirus B19 (HPV B19) - Erythema infectiosum (aka Fifth disease)
(HHV-6) or (HHV-7) - Exanthem Subitum
(aka roseola infantum aka Sixth disease)
Measles virus – measles (aka rubeola, aka hard measles)
Rubella virus - rubella (aka soft measles, aka German measles)
Host and Reservoir: Humans are the source of infection:
Variola virus, Varicella-zoster,
HPV B19, HHV-6, HHV-7, measles virus, rubella virus
seasonality??
chickenpox, erythema infectiosum, measles, rubella
transmitted in respiratory secretions (primary mode):
variola, varicella-zoster, HPV B19, measles
and rubella virus
transmitted in lesions (secondary mode):
variola, varicella-zoster viruses
transmitted in saliva:
HHV-6, HHV-7
Primary POE is the URT inhalation of respiratory droplets:
variola, varicella-zoster, HPV B19, measles,
rubella viruses or direct inoculation of conjunctiva.
Primary POE is the oropharynx:
HHV-6, HHV-7.
Primary attack rate is high – thus asymptomatic infections are uncommon/rare:
varicella- zoster, measles virus; variola virus
Virus in lesion and lesions are infectious:
smallpox, chicken pox
Lesion is immune-mediated (virus not present):
erythema infectiosum, exanthem
subitum
Active, life-long infection:
HHV-6, HHV-7
Latent infections with recrudescence of virus infections:
varicella-zoster, HHV-6,
HHV-7
Persistent infections:
HHV-6, HHV-7, measles (SSPE), rubella (congenital infection)
Prodrome:
smallpox, chickenpox (primary infection in adolescents and adults), erythema infectiosum (mild), measles, rubella (mild or absent)