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Micro > skin 12: summary > Flashcards

skin 12: summary Flashcards

1
Q

Need to know ALL names for agent/disease!

A

Variola virus – smallpox:
VZV - chickenpox and zoster
Human Parvovirus B19 (HPV B19) - Erythema infectiosum (aka Fifth disease)
(HHV-6) or (HHV-7) - Exanthem Subitum
(aka roseola infantum aka Sixth disease)
Measles virus – measles (aka rubeola, aka hard measles)
Rubella virus - rubella (aka soft measles, aka German measles)

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2
Q

Host and Reservoir: Humans are the source of infection:

A

Variola virus, Varicella-zoster,

HPV B19, HHV-6, HHV-7, measles virus, rubella virus

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3
Q

seasonality??

A

chickenpox, erythema infectiosum, measles, rubella

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4
Q

transmitted in respiratory secretions (primary mode):

A

variola, varicella-zoster, HPV B19, measles

and rubella virus

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5
Q

transmitted in lesions (secondary mode):

A

variola, varicella-zoster viruses

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6
Q

transmitted in saliva:

A

HHV-6, HHV-7

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7
Q

Primary POE is the URT inhalation of respiratory droplets:

A

variola, varicella-zoster, HPV B19, measles,

rubella viruses or direct inoculation of conjunctiva.

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8
Q

Primary POE is the oropharynx:

A

HHV-6, HHV-7.

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9
Q

Primary attack rate is high – thus asymptomatic infections are uncommon/rare:

A

varicella- zoster, measles virus; variola virus

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10
Q

Virus in lesion and lesions are infectious:

A

smallpox, chicken pox

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11
Q

Lesion is immune-mediated (virus not present):

A

erythema infectiosum, exanthem

subitum

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12
Q

Active, life-long infection:

A

HHV-6, HHV-7

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13
Q

Latent infections with recrudescence of virus infections:

A

varicella-zoster, HHV-6,

HHV-7

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14
Q

Persistent infections:

A

HHV-6, HHV-7, measles (SSPE), rubella (congenital infection)

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15
Q

Prodrome:

A 
smallpox, chickenpox (primary infection in adolescents and adults),
erythema infectiosum (mild), measles, rubella (mild or absent)
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16
Q

Acute Disease: Fever and a maculopapular rash:

A

variola virus, varicella-zoster, HPV B19, HHV-6, HHV-7, measles virus, rubella virus

17
Q

Acute Disease: Rash appears 1st on face, hand and forearms spreads to trunk, legs:

A

smallpox; rash/lesions are present on the palms of hands and soles of feet

18
Q

Acute Disease: Rash appears 1st on face spreads to trunk, limbs:

A

chicken pox, measles, rubella

19
Q

Acute Disease: Rash appears 1st on face, spreads to limbs (palms and soles), sometimes torso or
trunk:

A

erythema infectiosum

20
Q

Acute Disease: Rash appears 1st on face and trunk, spreads to limbs:

A

exanthem subitum

21
Q

Acute Disease: Fever defervesces then rash appears:

A

HHV-6 and HHV-7 (sometimes), variola virus,

HPV B19

22
Q

Acute Disease: Fever with rash:

A

chickenpox, measles, rubella

23
Q

Acute Disease: Arthropathy, arthralgia with fever, in adults, (more common in women) + rash:

A

HPV B19, rubella virus

24
Q

complications: of all?

A

Secondary bacterial infection and/or bacterial superinfection of skin or RT

25
Q

complication: Viral pneumonia, viral encephalitis

A

smallpox, varicella-zoster, measles

26
Q

complication: Aplastic crisis

A

Fifth disease

27
Q

complication: In utero infection

A

varicella-zoster, Fifth disease, HHV-6 (likely), measles, rubella

28
Q

complication: Congenital disease

A

varicella-zoster, HPV B19, measles, rubella

29
Q

complication: Reye’s syndrome

A

varicella-zoster - aspirin contraindicated

30
Q

complication: Diarrhea and pneumonia in malnourished populations

31
Q

complication: Otitis media in developed countries

32
Q

how to dx all viral exanthems

A

Clinical features, susceptibility, contact with infected person

33
Q

how to dx congenital infections

A

TORCH/STORCH/TORCHS test

34
Q

ddx: a person with a fever and maculopapular rash (excluding epidemiological factors such as age and seasonality):

A

all of above? + ECHOviruses, Coxsackie viruses enteroviruses 6871, arboviruses, Hepatitis B viruses, Dengue, Rocky Mountain Spotted Fever, Lyme Disease, Neisseria meningitidis, S. pneumoniae, scarlet fever, toxic shock syndrome

35
Q

ddx: a person with arthropathy:

A

HPV B19, rubella virus, Lyme Disease, rheumatoid arthritis

36
Q

Vaccine preventable -

A

smallpox, chickenpox, measles, rubella

37
Q

Post-exposure prophylaxis with vaccine to prevent disease -

A

chickenpox vaccine.

38
Q

Antiviral therapy -

A

chicken pox and zoster

39
Q

Immune globulin -

A

chicken pox

Micro (61 decks)

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