Skin Flashcards
What is eczema
- chronic atopic condition caused by defects in normal continuity of the skin barrier, leading to inflammation in the skin.
- genetic component, runs in families
Usual presentation of eczema
- usually presents in infancy with dry, red, itchy and sore patches of skin over flexor surfaces (inside of elbows and knees) and on face and neck. Flare ups
Mx of eczema
- maintenance: create an artificial barrier over skin to compensate for defective skin barrier.
- > emollients - as thick as tolerated + required to maintain the eczema. Thin creams = E45, Diprobase, Aveeno cream. Thick = 50:50 ointment, hydromol, cetraben
- Flares: thicker emollients, topical steroids. steroids = mild - hydrocortsone, moderate - eumovate, potent - betnovate
Pros and cons for steroids in eczema
pros: very good for settling down immune activity.
cons: thinning of skin (more prone to flares, bruising, tearing, stretch marks), enlarged blood vessels under surface of skin
Most common organism of opportunistic bacterial infection with eczema
staph aureus. Tx with flucloxacillin
Difference between blanching and non-blanching rash
Non-blanching rashes do not fade when a person presses on them. Occur due to bleeding beneath the surface of the skin.
- blanching rashes fade or turn white when a person applies pressure to them.
What are non-blanching rashes caused by? Types of non-blanching spots?
- bleeding under the skin
- petechia are small, non blanching, red spots on skin caused by burst capillaries.
- purpura are larger, non blanching, red-purple, macules or papules created by leaking of blood from vessels under the skin
Differential diagnosis of non-blanching rash
- meningococcal septicaemia or other bacterial sepsis
- HSP
- ITP - develops over several days in a well child
- Acute leukaemias - gradual development of petechiae + anaemia, lymphadenopathy
- Haemolytic uraemic syndrome
- Trauma - NAI, tight pressure on skin
- Viral ilness