skin Flashcards
how are skin lesions assessed
ABCD
asymmetry
border
colour
diameter
what is malignant melanoma
tumour arising from melanocytes
occurs in skin, eyes, oral cavity
5th most common cancer in UK
2nd most common cancer in adults between 25-49
risk factors for malignant melanoma
fair skin
sun exposure
sunbeds
are malignant melanomas graded
no - all high grade
how are melanomas staged
TNM
breslow thickness is the most important prognostic indicator
do melanomas respond well to chemo and radio
NO - prevention is key
what is acral melanoma
melanoma of palms, soles and under nails
not linked to sun expsoure
which is the most common non-melanoma skin cancer
basal cell carcinoma
clinical appearance of BCC
pearly appearance
nodule
central ulceration
can BCC spread?
yes
aggressive local spread but distant metastasis is rare
what is squamous cell carcinoma
the other main type of non-melanoma skin cancer
what are the risk factors for squamous cell carcinoma
fair skin
UV exposure
immunosuppresion - post renal transplant
chronic skin ulcers
clinical presentation of a SCC
irregular ketatotic tumour
ulcerates and crusts
grows faster than BCC
what is actinic keratosis/solar keratosis
common in elderly
brow, dry, scaly lesions on sun exposed sites
which non-melanoma is actinic keratosis related to any why
squamous cell carcinoma
actinic keratosis is pre-cancer/dysplasia
it is termed as carcinoma in situ as it is in one location and has the potential to spread
a small number of these cells can develop into SCC