Passmed Flashcards

1
Q

What is stigaliptin?

A

DDP-4 inhibitor

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2
Q

How do you investigate diabetes insipidus?

A

water deprivation test

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3
Q

What is the 1st line drug for hypertension in diabetes?

A

ACEi or A2RBs - regardless of age

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4
Q

In gestational diabetes, what happens if blood glucose targets are not met with metformin or diet?

A

add insulin (short acting)

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5
Q

What are the sick day rules for T1DM?

A

Aim to drink 3L of fkuid
Check blood glucose more regularly
Measure ketones
Do not substitute main meals for sugar containing foods

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6
Q

What is the treatment for myxoedemic coma (in hypothyroidism)?

A

IV thyroxine and hydrocortisone

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7
Q

What is the risk of over replacement with thyroxine?

A

osteoporosis

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8
Q

What can affect the absorption of levothyroxine?

A

Iron and calcium carbonate tablets

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9
Q

What are the features of a myxoedemic coma (hypothyroidism)?

A

Hypothermia, hyporeflexia, bradycardia, seizures

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10
Q

What are the features of pernicious anaemia?

A

Lethargy, pallor, SOB

Neurological - peripheral neuropathy, subacute combined degeneration of the spinal cord and neuropsychiatric disorders (progressive weakness, ataxia and paresthesia), memory loss, poor concentration, confusion, depression, irritability

glossitis, described as a red and enlarged tongue

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11
Q

Features of primary hyperaldosteronism

A

hypertension, hypernatraemia, and hypokalemia

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12
Q

What is given before an appendicectomy?

A

Prophylactic IV abx

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13
Q

What is the 1st line investigation for appendicitis in a female?

A

US abdo

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14
Q

What sign is classic of early appendicitis?

A

Peri umbilical pain

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15
Q

How does a ruptured AAA present?

A

Shock - low BP, tachycardia

Abdo pain radiating to back

Pulsatile mass

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16
Q

How does a complete hydatidiform mole present?

A

Uterus greater than expected

Abnormally high bhCG

17
Q

How does diverticulitis present?

A

Left lower quadrant pain (iliac fossa)

Low grade fever

Elderly patient

Hx of chronic constipation predisposes

Blood in stools

Raised inflammatory markers

18
Q

What causes pancreatitis?

A

Alcohol, gallstones, drug induced (mesalazine) for UC

19
Q

What is the presentation of mesenteric infarction?

A

Sudden onset severe abdo pain

Raised WCC and lactate

Hypertension, T2DM, AF risk factors

20
Q

What does an unrecordable blood glucose mean and when is this seen?

A

High blood sugar

DKA in children - drowsy and confused

21
Q

What is the significance of the whirlpool sign?

A

Seen on US - characteristic of ovarian torsion or volvulus

22
Q

What are the features of an Addisonian crisis?

A

Hyponatraemia
Hyperkalaemia
Hypoglycaemia

Surgery - precipitate acute adrenal deficiency

Unable to have steroids for prolonged period e.g. for polymyalgia rheumatica

23
Q

What is characteristic of a ruptured ovarian cyst?

A

Sudden onset unilateral pelvic pain precipitated by strenuous activity or intercourse

24
Q

How does an iliopsoas abscess present?

A

Fever

Pain on movement on hip joint

IV drug user

25
Q

What are the classic sx of IBS?

A

Abdominal pain
Bloating
Change in bowel habit