SKELETAL SYSTEM (PHYSIOLOGY) Flashcards
How Do Bones Develop?
▪ As an infant, most of your skeleton is cartilage.
▪ Cartilage is a strong flexible tissue.
▪ Over time the cartilage is replaced by solid bone,
usually complete by the time you stop growing.
▪ Not all cartilage is replaced in adults. Many joints contain cartilage, protecting the ends of bones (ears and the end of the nose is also cartilage).
As an infant, most of your skeleton is ____.
CARTILAGE
_____ is a strong flexible tissue.
CARTILAGE
How Strong are Bones?
▪ The structure of bones make it both strong and light weight.
▪ 20 % of an adults body weight is bone.
▪ Bone is made up of 2 minerals:
►Calcium
►Phosphorus
▪ The structure of bones make it both ___ & ___
both strong and
light weight.
___ % of an adults body weight is bone.
20%
▪ Bone is made up of 2 minerals:
►Calcium
►Phosphorus
Types of Bone Cells
OSTEOGENIC CELL
OSTEOBLAST
OSTEOCYTE
OSTEOCLAST
_____, are mitotically active stem cells found in the membranous periosteum and endosteum.
Osteogenic cell or osteoprogenitor cells
_____ bone-forming cells; synthesize and secrete collagen matrix and calcium salts
Osteoblasts
_____ mature bone cells; monitor and maintain the bone matrix
Osteocytes
______ giant bone-destroying cells
- Break down bone matrix for remodeling and release of calcium in response to parathyroid hormone
Osteoclasts
Bone remodeling is performed by both _____
osteoblasts and osteoclasts
____ is the process of bone formation
Ossification
- Occurs on hyaline cartilage models or fibrous membranes
- Long bone growth involves two major phases
Ossification
Two types of ossification
- Intramembranous ossification
- Endochondral ossification
(▪ Both types of bone formation result in compact and spongy bone.)
TYPES OF BONE FORMATION
►Bone formation and growth
►Intramembranous ossification
►Endochondral ossification
▪ Bone formation that occurs within connective tissue membranes
▪ Occurs when osteoblasts begin to produce bone within CT
▪ Bones of the skull
Intramembranous ossification
▪ Bone formation that occurs inside hyaline cartilage
▪ Cartilage model is replaced by bone.
Endochondral ossification
2 Classifications of Endochondral ossification
▪ Primary ossification center
▪ Secondary ossification center
bone formation in the diaphysis of a long bone
▪ Primary ossification center