INTEGUMENTARY SYSTEM Flashcards
- The _____ is the largest organ of the body that forms a physical barrier between the external environment and the internal environment that it serves to protect and maintain.
INTEGUMENTARY SYSTEM
- The ____ includes the epidermis, dermis, hypodermis, associated glands, hair, and nails.
INTEGUMENTARY SYSTEM
- In addition to its barrier function, this system performs many intricate functions such as body temperature regulation, cell fluid maintenance, synthesis of Vitamin D, and detection of stimuli.
INTEGUMENTARY SYSTEM
- The various components of this system work in conjunction to carry out these functions—for example, body temperature regulation occurs through thermoreceptors that lead to the adjustment of peripheral blood flow, degree of perspiration, and body hair.
INTEGUMENTARY SYSTEM
Components of Integumentary system
-skin
-nails
-hair
-cutaneous sense organ and glands
2 major tissue layers of skin
EPIDERMIS & DERMIS
CONSIST OF:
-superficial layer
-Stratified squamous epithelium
-Cornified or keratinized (hardened by keratin) to prevent water loss
-Avascular
-Most cells are keratinocytes
EPIDERMIS
The ___ prevents water loss and resists abrasion.
EPIDERMIS
CONSIST OF:
-Dense connective tissue
-Vascular
-on average the ____ is 10 to 20 times thicker than the epidermis.
-a layer of dense connective tissue depending on location (e.g. blood vessels, oil and sweat glands, nerves, hair follicles, and other structures.)
DERMIS
The ____ is responsible for most of the skin’s structural strength.
DERMIS
- The skin rests on the subcutaneous tissue, which is a layer of connective tissue.
e.g. areolar, adipose - not part of the skin, but it connects the skin to underlying muscle or bone.
DERMIS
- Functions as padding and insulation.
- The acceptable percentage of body fat varies from 21% to 30% for females and from 13% to 25% for males.
DERMIS
Layer of epidermis (thick hairless layer)
STRATUM CORNEUM
STRATUM LUCIDUM
STRATUM GRANULOSUM
DENDRITIC CELL
STRATUM SPINOSUM
MELANOZYT
STRATUM BASALE
BASEMENT MEMBRANE
DERMIS
- The _____ is a layer of the epidermis found in thick skin, such as the skin on the palms of the hands and the soles of the feet.
- Its presence in these areas serves a specific function related to the protective role of the skin.
STRATUM LUCIDUM
- Thick skin is subjected to more wear and tear and is exposed to harsher environmental conditions compared to thin skin.
- The _____ acts as an additional barrier, providing extra protection against mechanical stress, friction, and abrasion.
STRATUM LUCIDUM
- This layer consists of flattened, clear, dead keratinocytes (skin cells) that are tightly packed together. Its transparency is due to the absence of nuclei and other organelles in the cells.
- The presence of the _____ helps to reinforce the epidermis in areas of the body where additional protection is needed.
STRATUM LUCIDUM
- It contributes to the overall resilience and durability of thick skin, enabling it to withstand the rigors of daily activities and external factors.
STRATUM LUCIDUM
5 LAYERS OF EPIDERMIS
STRATUM BASALE
STRATUM SPINOSUM
STRATUM GRANULOSUM
STRATUM LUCIDUM
STRATUM CORNEUM
- stratum germinativum
-Deepest layer of epidermis
-Lies next to dermis
STRATUM BASALE
- Wavy borderline with the dermis anchors the two together
- Cells undergoing mitosis
- Daughter cells are pushed upward to become the more superficial layers
STRATUM BASALE
- Pricky layer
- Several cell layers thick
- Contain a weblike system of intermediate filaments
STRATUM SPINOSUM
- Granular layer
- Four to six layers thick
- Accumulates 2 types of granules:
->Keratohyaline granules
->Lamellar granules
STRATUM GRANULOSUM
– help to form keratin in the upper layer
KERATOHYALINE GRANULES
– contain water-resistant glycolipid for slowing water loss across the epidermis
LAMELLAR GRANULES
-Clear layer
- Formed from dead cells of the deeper strata
- Occurs only in thick, hairless skin of the palms of hands and soles of feet
STRATUM LUCIDUM
- Horny layer
- Outermost layer of epidermis
- Shingle-like dead cells are filled with keratin (protective protein prevents water loss from skin)
STRATUM CORNEUM
Excessive sloughing of stratum corneum cells from the surface of the scalp is called
DANDRUFF
In skin subjected to friction, the number of layers in the stratum corneum greatly increases, producing a thickened area called a
CALLUS (HARD SKIN)
Over a bony prominence, the stratum corneum can thicken to form a cone-shaped structure called a
CORN
Why is it that soles and palms have no hair?
The absence of hair on the soles of the feet and the palms of the hands is primarily due to evolutionary adaptation and functional specialization.
Grip and Traction: The palms and soles are areas that come into direct contact with surfaces during activities such as walking, climbing, and grasping objects.
- The absence of hair allows for better grip and traction, enhancing tactile sensitivity and improving the ability to perform tasks that require dexterity and precision.
Sensitivity: Hair follicles contain nerve endings that contribute to sensory perception. The absence of hair on the palms and soles increases the sensitivity of these areas to touch, pressure, and temperature changes, enabling finer sensory discrimination and enhancing tactile feedback.
Hygiene: Hair follicles can trap dirt, debris, and microorganisms, potentially leading to hygiene-related issues such as infection or irritation. The absence of hair on the palms and soles reduces the likelihood of debris accumulation and facilitates easier cleaning and maintenance of these areas.
Heat Regulation: Hair acts as an insulating layer that can help regulate body temperature by trapping heat close to the skin. However, excessive hair on the palms and soles could interfere with efficient heat dissipation, which is essential for maintaining optimal thermal balance, particularly during activities that involve significant physical exertion.
Overall, the absence of hair on the palms and soles represents an evolutionary adaptation that optimizes tactile sensitivity, grip, hygiene, and thermoregulation, enabling effective functioning of these specialized regions of the body.
Cells in the Epidermis
KERATINOCYTES
MELANOCYTES
DENDRITIC (Langerhans) CELLS / INTRAEPIDERMAL CELLS
TACTILE (Merkel) CELLS
- Produce keratin, a fibrous protein that helps give the epidermis its protective properties
- Arise in the deepest part of the epidermis, stratum Basale
KERATINOCYTES
- Spider-shaped epithelial cells
- Synthesize melanin pigment
- Found in the deepest part of the epidermis
MELANOCYTES
- Arise from bone marrow and migrate to the epidermis
- Ingest foreign substances
- Key activators of our immune system
Dendritic (Langerhans) Cells / Intraepidermal cells
- Present at the epidermal-dermal junction
- Functions as sensory receptor for touch
Tactile (Merkel) Cells
TWO LAYERS OF DERMIS
PAPILLARY LAYER
RETICULAR LAYER
- Areolar connective tissue
- Collagen and elastic fibers form a loosely woven mat
- Projections called dermal papillae
->Some contain capillary loops
->Others house pain receptors and touch receptors called tactile or Meissner’s corpuscles
Papillary layer (upper dermal region)
The ___ contain many blood vessels.
The ___ in the palms of the hands, the soles of the feet, and the tips of the digits are arranged in parallel, curving ridges that shape the overlying epidermis into fingerprints and footprints.
DERMAL PAPILLAE
Downward projections of epidermis is the called the
rete ridges
- 80% of the thickness of the dermis
- Dense fibrous connective tissue
- Cleavage (tension lines) – important to surgeon
- Flexure lines – dermal folds that occur at or near joints
RETICULAR LAYER
– important to surgeon
- Langer lines of skin tension, or sometimes called ____, are topological lines drawn on a map of the human body.
- They are parallel to the natural orientation of collagen fibers in the dermis, as well as the underlying muscle fibers.
CLEAVAGE (TENSION LINES)
– dermal folds that occur at or near joints
- Found in the fingers and toes, etc. are places where the dermis has folds to accommodate joint movement.
FLEXURE LINES
An incision made ____ with these lines tends to gap less and produce less scar tissue.
PARALLEL
NORMAL SKIN COLOR DERMINANTS
MELANIN
CAROTENE
HEMOGLOBIN
-Polymer made of tyrosine amino acids
>Pheomelanin – Yellow to red
>Eumelanin – brown to black
MELANIN
____ is produced by melanocytes and the melanin is packaged into vesicles called melanosomes, which move into the cell processes of melanocytes.
MELANIN
-Precursor of Vitamin A needed for vision
-Lipid-soluble
-Orange-yellow pigment from some vegetables
-Accumulates in the stratum corneum and in fatty tissue of the hypodermis
CAROTENE
-Red coloring from blood cells in dermal capillaries
-Oxygen content determines the extent of red coloring
-A decrease in blood flow, as occurs in shock, can make the skin appear pale.
-A decrease in the blood O2 content produces a bluish color of the skin, called cyanosis.
HEMOGLOBIN
A ____, as occurs in shock, can make the skin appear pale.
A _____ content produces a bluish color of the skin, called ____.
- decrease in blood flow,
- decrease in the blood O2
- cyanosis.
8 Alterations in Skin Color
CYANOTIC
REDNESS (ERYTHEMA)
PALLOR (BLANCHING)
JAUNDICE (YELLOWING)
DEPIGMENTATION
BRONZING (HYPERPIGMENTATION)
ALBINISM
BRUISES