skeletal,smooth & cardiac muscle Flashcards

1
Q

what is the main structural difference between skeletal & smooth muscle?

A

skeletal is striated , smooth is non-striated

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2
Q

where is smooth muscle located?

A

located in the lining of hollow organs, and blood vessels

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3
Q

where is skeletal muscle located & where is cardiac muscle located

A

skeletal= on the peripheral

cardiac= centrally (c for centrally in the word cardiac)

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4
Q

compare the nucleus number in skeletal muscle & in cardiac

A

skeletal- multinucleated

cardiac- single nuclear

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5
Q

how is skeletal muscle organised ?

A

bundles of muscles fibres encased in connective tissue sheaths

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6
Q

after skeletal muscle injury, what cells are used to replace the damaged cells?

A

satellite cells

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7
Q

do damaged skeletal muscle cells ever fully recover?

A

no
(satellite cells help replace damaged cells tho)

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8
Q

what is hypertrophy?

A

increase in muscle size due to fibre size increase

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9
Q

what is a sacromere

A

repeating unit(allows skeletal muscles to performs their function)

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10
Q

describe the filaments actin & myosin in terms of there thickness

A

myosin= thick filament

actin= thin filament

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11
Q

what are the 2 components of sacromere ?

A

actin & myosin filaments

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12
Q

what is the difference between the Z-line of a sacromere & the M-line of a sacromere ?

A

Z-line: proteins which holds actin filaments in position

M-line: holds myosin filaments in position

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13
Q

role of titan filaments in skeletal muscle

A

hold myosin filaments in the correct ALIGNMENT

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14
Q

in skeletal muscle, when ATP binds to myosin, what happens?

A

detaches the cross bridge formed between actin & myosin

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15
Q

in skeletal muscle, which 2 receprots are triggered that cause the release of Ca+ ?

A

DHP receptor first (small quantity released)

ryanodine receptor (larger quantity)

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16
Q

what is sarcoplasm?

A

cytoplasm of muscle cell (sarcolemma is the cell membrane of skeletal muscle)

17
Q

how is Ca+ taken back up by the sarcoplasmic retiuculum in skeletal muscle ?

A

calcium ATPase

18
Q

which molecule is vital for muscle relaxation?

19
Q

what is a motor unit?

A

it is a motor neuron & all the muscle fibres it innervates

20
Q

why are motor units scattered about muscle?

A

if one motor unit fails, the other can compensate

21
Q

what is the difference between force of muscle and load on muscle?

A

force built up within a muscle is tension of muscle

load = force exerted on a muscle

22
Q

if a muscle contracts and the muscle length remains the same, what is the term used to describe this?

A

isometric contractions

23
Q

if a muscle contracts and the muscle length shortens, what is the term used to describe this?

A

isotonic contractions

24
Q

difference between isometric and isotonic contractions and give examples of each

A

isometric = muscle contracts but muscle length stays the same e.g weightlifting

isotonic = muscle contracts but muscle length shortens e.g running

25
if a muscle contracts and the muscle length icnreases, what is the term used to describe this
lenghthening
26
which contraction , isometric or isotonic has a faster response time ?
isometric (length stays the same)
27
what does the time of contraction depend on?
speed of release of Ca+
28
what is the LATENT period in muscle contraction?
time before myosin-actin cross bridge forms (time before excitation-contraction )
29
what is optimal length, in terms of muscle contraction?
muscle length for greatest isometric tension
30
what are the causes of fatigue during high intensity exercise then causes of faitgue in low intesity exercise
high intensity= increase in things low intensity= decrease in things (e.g decrease in glycogen)
31
what makes a fast twitch muscle fast and a slow twitch muscle slow?
myosin has high ATPase activity slow twitch- myosin has low ATPase activity
32
what colour of fibre are oxidative fibres and glycolytic fibres and how big is their diameters
oxidative= red fibres with low diameter glyoclytic fibres =white fibres with large diameter
33
if a muscle is not used, what does this lead to?
disuse atrophy
34
what does destruction of the nerve/NMJ lead to?
denervation atrophy
35
what does exercise cause in terms of muscle mass?
hypertrophy (increase muscle mass and increase fibre mass)
36
in smooth muscles, what are the filaments attached to?
dense bodies