Skeletal muscle disorders Flashcards
What is gout?
An inflammatory disease cuased by deposits of monosodium urate crystals in joints.
True or False.
Gout can produce Arthritis.
True, repeated gouty attacks can cause the detsruction of joints.
Stage 1 of gout.
High uric acid levels (no sympthoms).
Stage 2 of gout.
Sympthons start to occur, painful gout attacks.
Stage 3 of gout.
Periods of remission between gout attacks.
Treatments of gout.
- Inhibit urate production (xanthine oxidase).
- Normalize renal urate excretion.
- Metabolize urate (allatoin).
How is called the waste product of the destruction of myocytes?
Myoglobin.
Rhabdomyolisis produce the destruction of the muscles, but it can also affects:
Kidneys, because of the high concentration of myoglobin along the renal tubules.
How often does the cortical bone changes?
Every 3-4 years.
PTH is produced in response to:
Low levels of Ca, it increase bone reabsorption
Calcitonin is produced by tyroid gland in response to:
High levels of Ca, it promotes bone formation.
Osteoporosis treatment.
- Biphosphonates (alenodrate).
- Denosumab (inhibits osteoclasts).
