Parkinson disease Flashcards

1
Q

Which structure is the most affected in Parkinson disease?

A

Substantia nigra.

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2
Q

What’s the function of substancia nigra?

A

Sintetize dopamine.

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3
Q

Which gene has an important function in Parkinson disease?

A

PARK 1.

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4
Q

What is the function of PARK1?

A

Produces the accumulation of a-synuclein (waste product).

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5
Q

¿Cuáles son las principales manifestaciones clínicas en Parkinson?

A

BRIT (Bradicinesia, Rigidez, Inestabilidad, Temblor en reposo).

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