Parkinson disease Flashcards
1
Q
Which structure is the most affected in Parkinson disease?
A
Substantia nigra.
2
Q
What’s the function of substancia nigra?
A
Sintetize dopamine.
3
Q
Which gene has an important function in Parkinson disease?
A
PARK 1.
4
Q
What is the function of PARK1?
A
Produces the accumulation of a-synuclein (waste product).
5
Q
¿Cuáles son las principales manifestaciones clínicas en Parkinson?
A
BRIT (Bradicinesia, Rigidez, Inestabilidad, Temblor en reposo).