Skeletal GW

Question 1

RPs and dose

Answer 1

99mTc medronate (MDP)
99mTc oxidronate (HDP)

20-30 mCi

Question 2

Which RP has faster blood clearance

Answer 2

MDP

Question 3

Which RP has greater bone uptake

Answer 3

HDP

Question 4

What % is excreted

Answer 4

50% excreted renally

Question 5

Localization depends on what

Answer 5

Blood flow
Rate of bone remodeling

Question 6

What kind of bone activity shows increased uptake

Answer 6

Osteoblastic (bone building)

Question 7

What kind of bone activity shows decreased uptake

Answer 7

Osteolytic (bone destruction)

Question 8

Method of localization

Answer 8

Ion exchange of phosphorous groups from tracer with hydroxyapetite bone crystal

Question 9

How many counts for each spot view technique to create whole skeleton

Answer 9

500k-1 million

Question 10

Amount of counts for moving whole body acquisition technique

Answer 10

More than 1.5 million counts each view

Question 11

Normal tracer distribution

Answer 11

Sacroiliac joints, anterior iliac crest, sternum, nasopharyngeal area, shoulder joints, spine, epiphyseal plates of long bones and costochondral junctions in kids

Question 12

Cellulitis uptake

Answer 12

Hot
Hot
Not

Question 13

Osteomyelitis uptake

Answer 13

Hot
Hot
Hot

Question 14

Injection to imaging time

Answer 14

1. Flow - Immediately
2. Blood pool - Within 10 minutes
3. 2-4 hours
4. 24 hour

Question 15

Injection to imaging time for WB

Answer 15

2-4 hours