Interventional Drugs GW

Question 1

Captopril dose for renovascular hypertension evaluation

Answer 1

25-50 mg oral

given 1 hr prior to tracer

Question 2

Anticoagulants

Answer 2

ACD
Heparin

Question 3

Acetazolamide (Diamox) amount given and how

Answer 3

1g in 10 mL sterile water
IV over 2 minutes

Question 4

Adenosine plasma half life

Answer 4

<10 seconds

Question 5

Dobutamine plasma half life

Answer 5

2 minutes

Question 6

Dipyridamole plasma half life

Answer 6

35-45 minutes

Question 7

Adenosine dose

Answer 7

140 ug/kg/min for 6 minutes

Or 0.84 mg/kg

Question 8

Atropine dose

Answer 8

Bump for dobutamine

0.25 - 0.5 mg
1-2 mg max

Question 9

Ascorbic acid use

Answer 9

RBC labeling and HDP preparation

Question 10

CCK dose

Answer 10

0.02 ug/kg

Question 11

Cimetidine (Tagamet) dose and use

Answer 11

To prevent Pertechnetate from clearing out of gastric mucosa
-Used in Meckels

300mg/kg adults
20mg/kg peds
*IV given 1 hr before tracer, oral given over 2 days prior

Question 12

Dipyridamole (persantine) dose

Answer 12

0.57 mg/kg

IV over 4 minutes

Question 13

Dobutamine dose

Answer 13

Incremental dose rate every 3 mins
15 ug/kg/min up to
40ug/kg/min

Question 14

Enalaprilat (Vasotec) dose and use

Answer 14

For renovascular hypertension evaluation

Adult: 0.04 mg/kg (max 2.5 mg)
in 10 mL saline
IV over 5 minutes

Question 15

Dobutamine antidote

Answer 15

Esmolol

Question 16

Furosemide (lasix) dose

Answer 16

Adult: 20-40 mg IV over 1 minute

Peds: 0.5-1 mg/kg IV over 1-2 mins

Question 17

Glucagon dose and use

Answer 17

Meckels
- relaxes smooth muscle and slows down peristalsis to allow tracer to remain stationary for longer

Adult: 0.5 mg (0.25-2)
Peds: 5 ug/kg given IV or IM
*given 10 minutes AFTER tracer

Question 18

SSKI (super saturated potassium iodide) or Lugol’s solution dose

Answer 18

Adult: 130 mg
Peds: 65 mg

Question 19

Morphine dose

Answer 19

0.04 mg/kg (2-4.5)
In 10 mL saline
IV over 2 minutes

Question 20

Morphine antidote

Answer 20

Naloxone

Question 21

Pentegastrin (Peptavalon) use and dose

Answer 21

Meckels
- stimulates gastric secretions, increasing tracer secretion in stomach

6 ug/kg subcutaneously
15-20 mins before tracer

Question 22

Phenobarbital (Luminal) dose and use

Answer 22

To differentiate biliary atresia from other causes of jaundice
-it enhances excretion of tracer if ducts are patent

5mg/kg/day orally for 5 days

Question 23

Ranitidine (Zantac) dose and use

Answer 23

Ectopic gastric mucosa

100-150 mg twice daily

Question 24

Regadenoson dose

Answer 24

0.4 mg in 5 ml

Question 25

rhTSH dose

Answer 25

0.9 mg 2 total
IM injections on 2 consecutive days

Question 26

Vitamin B12 (Cyanoject, Cyomin)

Answer 26

Schilling’s test

1mg IM

Question 27

CCK serum half life

Answer 27

2.5 minutes

Question 28

Morphine serum half life

Answer 28

3-6 hours

Question 29

CCK is contraindicated if

Answer 29

Pt had morphine
Known sensitivity
Intestinal obstruction

Question 30

Morphine is contraindicated with

Answer 30

Premature neonates, patients with respiratory depression, morphine allergy, acute pancreatitis

Question 31

Phenobarbital contraindicated in patients with

Answer 31

Respiratory depression and/or
Known allergy to barbiturates

Question 32

Dipyridamole (persantine) contraindications

Answer 32

Bronchospasm, pulmonary disease, active wheezing, hypotension, severe mitral valve disease

MI within 2 days, unstable angina within 48 hours, severe aortic stenosis, severe obstructive hypertrophic cardiomyopathy, and severe orthostatic hypotension

Question 33

Dipyridamole (persantine) administration

Answer 33

0.142 mg/kg/min
(0.56 mg/kg in 50 mL saline)

Infused over 4 minutes

Question 34

Dipyridamole peak effect takes place when

Answer 34

2-3 minutes after infusion has ended

Question 35

When to inject tracer with dipyridamole

Answer 35

3-5 minutes after the infusion has ended

Question 36

Maximum plasma concentration of regadenoson occurs within _____ after injection

Answer 36

1-4 minutes