Skeletal and nervous tissue Flashcards

1
Q

What are the characteristics of skeletal muscles?

A

They are striated, strong, quick, voluntary, multinucleated and large

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2
Q

What is the arrangement of muscles? from smallest to largest grouping

A

sacromere–> myofibrils–> muscle fiber–> fascicle–> muscle

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3
Q

What is a sacromere?

A

A contractile unit of muscle that is made of actin and myosin myofilaments

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4
Q

What surrounds the muscle fibers?

A

endomysium

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5
Q

What surrounds the fascicles?

A

perimysium

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6
Q

What surrounds the muscle?

A

epimysium

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7
Q

What composes the myosin component of a sacromere?

A

2heavy chains with globular heads- there are actin binding sites with ATPase domains
2 light chains

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8
Q

What holds the myosin of a sacromere in place?

A

They are held by Titin proteins to the z-disk

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9
Q

What composes the actin component of the sacromere?

A

f-actin monomers(globular) that bind together and form double stranded chains
nebulin will determine length of filament
tropomyosin strands wrap between actin strands and troponin sits on these strands to cover actin binding sites

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10
Q

What are the 5 components of the sacromere?

A

The m-line, z-disk, H band, A band and I band

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11
Q

What is the m-line?

A

found in the sacromere and is the attachment site for myosin

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12
Q

What is the z-disk?

A

found in the sacromere- this is the site between sacromeres where actin and titin bind

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13
Q

What is the H band?

A

Found in the sacromere- The space on either side of the m-line where there is no actin

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14
Q

What is the A band?

A

Found in the sacromere- Distance from the end of one myosin head to the head of the opposite myosin

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15
Q

What is the I band?

A

Found in the sacromere- Space on either side of the z-disk where there is no myosin

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16
Q

What is the only band in the sacromere that will not change distance?

A

The A band since the actin is sliding along the myosin to create contraction

17
Q

How does muscle contraction work?

A

Myosin must bind to actin- Calcium is released from the SR and will bind to troponin to induce a confirmational change and allows actin to bind to myosin heads and slide past eachother

18
Q

What is the sarcolemma?

A

membrane around each muscle cell

19
Q

What is the transverse tubules?

A

membrane system penetrating the muscle cell to convey electrical impulses from sacrcolemma into the cell

20
Q

What is a multipolar neuron?

A

multiple dendrites and one axon

21
Q

What is a bipolar neuron?

A

single dendrite (multiple extensions) with one axon

22
Q

What is a pseudounipolar neuron?

A

One cell process with a single dendrite branch and one axon branch

23
Q

What is the arrangement of neurons?

A

Axon–> fascicle–>nerve

24
Q

What surrounds the axon?

A

endoneurium

25
Q

What surrounds the neuron fascicle?

A

perineurium

26
Q

What surrounds the nerve?

A

epineurium

27
Q

What is a schwann cell?

A

surounds axon and creates myelin sheath in the PNS - will wrap around one part of one axon

28
Q

What is an oligodendrocyte?

A

surrounds axon and creates myelin sheath in the CNS- will wrap around a part of many axons

29
Q

What is the myelin sheath?

A

circumferential layers of myelin allowing for faster signal conduction velocity

30
Q

What is the neuromuscular junction?

A

Skeletal muscles innervated by peripheral a-motor neurons from the anterior horn of spine