Skeletal and nervous tissue Flashcards
What are the characteristics of skeletal muscles?
They are striated, strong, quick, voluntary, multinucleated and large
What is the arrangement of muscles? from smallest to largest grouping
sacromere–> myofibrils–> muscle fiber–> fascicle–> muscle
What is a sacromere?
A contractile unit of muscle that is made of actin and myosin myofilaments
What surrounds the muscle fibers?
endomysium
What surrounds the fascicles?
perimysium
What surrounds the muscle?
epimysium
What composes the myosin component of a sacromere?
2heavy chains with globular heads- there are actin binding sites with ATPase domains
2 light chains
What holds the myosin of a sacromere in place?
They are held by Titin proteins to the z-disk
What composes the actin component of the sacromere?
f-actin monomers(globular) that bind together and form double stranded chains
nebulin will determine length of filament
tropomyosin strands wrap between actin strands and troponin sits on these strands to cover actin binding sites
What are the 5 components of the sacromere?
The m-line, z-disk, H band, A band and I band
What is the m-line?
found in the sacromere and is the attachment site for myosin
What is the z-disk?
found in the sacromere- this is the site between sacromeres where actin and titin bind
What is the H band?
Found in the sacromere- The space on either side of the m-line where there is no actin
What is the A band?
Found in the sacromere- Distance from the end of one myosin head to the head of the opposite myosin
What is the I band?
Found in the sacromere- Space on either side of the z-disk where there is no myosin