SJS/TEN Flashcards
1
Q
Describe Stevens-Johnson syndrome or Toxic Epidermal Necrolysis
A
It is life-threatening exfoliative mucocutaneous disease
2
Q
Epidermal separation of SJS and TEN
A
SJS = <10% of body surface area
TEN = >30% of body surface area
3
Q
Features of SJS
A
Mucosal lesions
Epidermal separation
Fever
Skin tenderness
4
Q
Features of TEN
A
Mucosal lesions
Epidermal separation
Fever
Skin tenderness
Hypotension
Decreased consciousness
5
Q
Biopsy of SJS/TEN
A
SJS = Degeneration of basal layer of the epidermis
TEN = Full-thickness eosinophilic epidermal necrosis
6
Q
How to treat SJS/TEN?
A
Short course of intravenous immunoglobulin (IVIG)