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Dermatology > Dermatitis Herpetiformis > Flashcards

Dermatitis Herpetiformis Flashcards

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Dermatology Board Prep flashcards
1
Q

What is DH?

A

Autoimmune blistering disorder
Males > females

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2
Q

DH associated with?

A

Celiac disease

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3
Q

Pathogenesis of DH

A

Gliadin is the antigen, the body makes IgA, and then this antibody loses its way and attack reticulin in the skin forming small grouped vesicles/ bullae (supepidermal blister)

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4
Q

Direct immunofluorescence

A

granular deposits of IgA in the tips of dermal papillae

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5
Q

Skin biopsy

A

Subepidermal blisters
Neutrophil microabscess in the dermal papillae

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6
Q

Tx

A

Resolves with gluten-free diet

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Dermatology (8 decks)

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