Lichen Planus Flashcards

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1
Q

What is lichen planus?

A

Lichen means tree moss
Planus means flat
Flat topped skin rash which is immune mediated disorder
It can affect the mucous membranes

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2
Q

Dermoepidermal junction is _________ waved

A

Smooth waved

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3
Q

Pathogenesis of lichen planus

A

Normal healthy keratinocytes present antigens by MHC-1. Cytotoxic T cells kill them and this then starts to spread from stratum basale to stratum granulosum. Keratinocytes start to proliferate and increase in size called Hypergranulosis

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4
Q

Drugs that trigger lichenoid reaction

A

Antimalarial drugs

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5
Q

Symptoms of Lichen planus

A

Cutaneous LP
Oral LP
Both LP
6 Ps
Wickham Striae

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6
Q

6 Ps

A

Planar
Pruritic
Purple
Papular (<5 mm)
Plaque (>5 mm)
Polygonal

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7
Q

Diagnosis of LP

A

Saw tooth
Hypergranulosis
Appearance

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8
Q

Treatment of LP

A

Corticosteroids
Remove the triggering factor in lichenoid rxn

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