Sjorgen's syndrome

Question 1

Sjogren’s syndrome can arise as a secondary disease as a result of which two diseases?

Answer 1

RA
SLE
Systemic sclerosis

Question 2

List three features of Sjorgen’s

Answer 2

Most commonly: dry eyes and mouth
 ↓ tear production → dry eyes 
↓ salivation → xerostomia 
Bilateral parotid swelling 
Vaginal dryness → dyspareunia 
Polyarthritis 
Raynaud’s 
Bibasal pulmonary fibrosis 
Vasculitis 
Myositis

Question 3

Name two autoantibodies that are positive in Sjorgen’s

Answer 3

RA, ANA

Question 4

Two investigations for sjorgen’s?

Answer 4

Tear test= Schirmer
Autoantibodies
Parotid biopsy

Question 5

Two treatments for sjorgen’s?

Answer 5

 Artificial tears
 Saliva replacement solutions
 NSAIDs and hydroxychloroquine for arthralgia
 Immunosuppression for severe systemic disease

Question 6

What is a common initial presenting complaint in people with Sjorgen’s?

Answer 6

renal tubular acidosis- polyuria, polydipsia, urine dip low pH

Question 7

Define Sjorgen’s

Answer 7

a chronic autoimmune condition characterized by degeneration of the salivary and lachrymal glands, causing dryness of the mouth and eyes.