Signaling Pathways

Question 1

cAMP?

Answer 1

FLAT ChAMP = FSH, LH, ACTH, TSH, CRH, hCG, ADH (V2 receptor), MSH, PTH, glucagon, calcitonin, GHRH

Question 2

cGMP?

Answer 2

ANP, NO (think vasodilators)

Question 3

IP3?

Answer 3

GGOAT = GnRH, GHRH, Oxytocin, ADH (V1 receptor), TRH, histamine (H1), angiotension II, gastrin

Question 4

Steroid hormones?

Answer 4

VETTT CAP = Vitamin D, Estrogen, Testosterone, T3/T4, Cortisol, Aldosterone, Progesterone

Question 5

Intrinsic tyrosine kinase (MAP kinase pathway)?

Answer 5

Insulin, IGF-1, FGF, PDGF, EGF (think growth factors)

Question 6

Receptor-assoc tyrosine kinase (JAK-STAT pathway)?

Answer 6

PIG = Prolactine, Immunomodulators (e.g. cytokines IL-2, 6, 8, IFN), GH (think acidophiles and cytokines)