Oxidative Phosphorylation Poisons

Question 1

Insecticides?

Answer 1

Rotenone

Question 2

Created by Streptomyces?

Answer 2

Antimycin A, oligomycin

Question 3

ETC inhibitors?

Answer 3

Rotenone, antimycin A, CN-, CO

Question 4

ATP synthase inhibitors?

Answer 4

Oligomycin

Question 5

Uncoupling agents?

Answer 5

2,4-DNP, aspirin

Question 6

Blocks complex I?

Answer 6

Rotenone

Question 7

Blocks complex III?

Answer 7

Antimycin A

Question 8

Blocks complex IV?

Answer 8

CN-, CO

Question 9

Blocks complex V?

Answer 9

Oligomycin

Question 10

Result of uncoupling agents?

Answer 10

Fever–due to carrying protons across mitochondrial membrane leading to rapid O2 consumption without generation of ATP, resulting in heat