Side Effects To Memorise Flashcards

1
Q

Rifampicin

A

Orange tears/urine

Hepatitis

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2
Q

Isoniazid

A

Neuropathy

Hepatitis

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3
Q

Pyrazinamide

A

Hepatitis

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4
Q

Ethambutol

A

Optic neuritis

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5
Q

Phenytoin

A

Cerebellar syndrome, acne, coarse face, gum hypertrophy, hirsutism, inhibit COCP

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6
Q

Carbamazepine

A

Rash, dizziness, hyponatraemia, hair thinning, inhibit COCP, agranulocytosis

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7
Q

Sodium valproate

A

Tremor, weight gain, hair thinning, teratogenic

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8
Q

Lamotrigine

A

Rash (Stevens-Johnson syndrome)

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9
Q

SSRI

A

Fluoxetine, citalopram, sertraline

Nausea, low libido, withdrawal, insomnia, hyponatraemia

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10
Q

TCA

A

Amitriptyline

Anti cholinergic, anti histaminergic, anti alpha adrenergic, hyponatraemia (SIADH), arrhythmia

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11
Q

MOA Inhibitors

A

Selegiline

Hypertension, hepatocellular jaundice, hyperthermia

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12
Q

ACE Inhibitors

A

Dry cough, postural hypotension, renal failure (renal artery stenosis), angioedema of the tongue, hyperkalaemia, profound hypotension when started

Check UE’s before and 2 weeks after starting

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13
Q

Calcium channel blocker

A

Amlodipine, nifedipine, verapamil

Ankle oedema, headache, flushing, dizziness

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14
Q

Beta blocker

A

Diabetes risk, impotence, bradycardia, fatigue, cold hands and feet, sleep disturbance

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15
Q

Alpha blockers

A

Anti alpha adrenergic effects

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16
Q

Diuretics

A

Dehydration, hypotension, hyperuricaemia, hypokalaemia (except K sparing eg. Epleronone, spironolactone), hyponatraemia, hypomagnesia

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17
Q

Loop diuretics

A

Furosemide, bumetanide

Hypocalcaemia

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18
Q

Thiazide diuretics

A

Indapamide, chlorothiazide

Hypercalcaemia

19
Q

Potassium sparring diuretics

A

Eplerenone, spironolactone

Hyperkalaemia, gynaecomastia

20
Q

Sulfalazine

A

DMARD

Myleosuppression, oligospermia, hepatitis, SJ syndrome, erythema nodosum, renal disorders, discoloured urine

21
Q

Chloroquine

A

DMARD

Retinopathy, tinnitus, myopathy

22
Q

Methotrexate

A

DMARD

Hepatic toxicity, pulmonary toxicity, myelosupression, mucositis

23
Q

TNF antagonists

A

DMARD

Infliximab, etanercept

Infusion reaction (including anaphylaxis), infections (TB reactivation), autoimmune reactions, blood disorders

24
Q

Cyclophosphamide

A

DMARD

Haemorrhagic cystitis, myelosupression, alopecia

25
Q

Insulin

A

Hypoglycaemia, fat hypertrophy at injection site, hypokalaemia, weight gain

26
Q

Metformin

A

Weight loss, lactic acidosis, metallic taste, GI disturbance, B12 deficiency

27
Q

Glicazide

A

Sulfonylurea

Hypoglycaemia, weight gain

28
Q

Pioglitazone

A

Thiazolidinediones

Fluid retention- heart failure and oedema, hepatotoxicity, fractures

29
Q

Sitagliptin

A

DPP4 Inhibitors

Pancreatitis

30
Q

Empagliflozin

A

SGLT2 Inhibitors

UTI, thrush, ketoacidosis, weight loss, may increase risk of amputation

31
Q

Antipsychotics

A

Anti dopaminergic, anti cholinergic, anti histaminegic, anti alpha adrenergic effects

32
Q

Clozapine

A

Agranulocytosis

33
Q

Chlorpromazine

A

Cholestatic jaundice

34
Q

Haloperidol

A

Prolonged QT interval, temperature dysregulation

35
Q

Lithium

A

Toxicity (tremor, ataxia, dysarthria), coma, convulsions, hypotension, diarrhoea, hypothyroidism, diabetes insipidus

36
Q

Steroids

A

Diabetes risk, Cushingoid appearance, psychosis, osteoporosis, hypokalaemia, hyperglycaemia, infections, leukocytosis, risk of a vascular necrosis

37
Q

Azathioprine

A

Myelosupression

38
Q

Cyclosporine

A

Immunosuppressant eg. RA

tremor, interstitial nephritis, gum hyperplasia, burning in hands and feet, hypertrichosis (excessive body hair)

39
Q

Levodopa

A

Nausea, red urine, postural hypotension, dyskinesias, on off phenomena, wearing odd effects

40
Q

PPI

A

Omeprazole

Tinnitus, GI disturbance, headache, hyponatraemia, hypomagnesia

41
Q

Amiodarone

A

Thyroiditis (hypo or hyper), pulmonary fibrosis, peripheral neuropathy, myopathy, grey skin, photosensitivity, hepatitis, metallic taste

42
Q

Digoxin toxicity

A

Xanthopsia (yellow/ orange tint to vision), GI distress, any arrhythmia

43
Q

Adenosine

A

Flushing, sense of impending doom

44
Q

Metoclopramide

A

Drug induced Parkinson’s

Galactorrhoea