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Prescribing and Pharmacology > Cytochrome P450 > Flashcards

Cytochrome P450 Flashcards

1
Q

Cytochrome P450 Substrates

A

COWPATS

Ciclosporine, carbamazepine, citalopram 
Oral contraceptive pill
Warfarin 
Phenytoin, proteas inhibitors 
Acetylcholinesterase inhibitors eg. Donepezil 
Theophylline 
Statins, steroids
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2
Q

Cytochrome P450 Inducers

A

Reduce concentration of drugs metabolised by cytochrome P450 system

CRAPS

Carbamazepine
Rifampicin 
bArbituates 
Phenytoin 
St Johns Wart
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3
Q

Cytochrome P450 Inhibitors

A

Increase concentration of the drugs metabolised by the cytochrome P450 system

Sodium valproate 
Cirpofloxacin 
Sulphonamides 
Cimetidine/omeprazole 
Anti fun gals, Amiodarone
Isoniazid 
Erythromycin, clarithromycin 
Grapefruit juice
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Prescribing and Pharmacology (17 decks)

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