Side Effects Flashcards

1
Q

Insulin

A

DERM: localized urticarial lesions (usually disappear), lipodystrophy of subcutaneous fat, pruritus; ENDO: hypoglycaemia due to excess; insulin resistance; OTHER: hypersensitivity reactions, incl. anaphylactic shock, angioneurotic edema

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2
Q

Baclofen; Skeletal Muscle Relaxant

A

A

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3
Q

Acetaminophen (Tylenol, APAP, Apsirin, etc.); Nonopioid Analgesic: p-Aminophenol, Nonsalicylate Analgesic

OTC; Preg Cat B

A

DERM: erythematous reactions, urticaria; HEM: anemia, leukopenia, neutropenia, pancytopenia, hemolytic anemia, methemoglobinemia (rare); HEP: jaundice

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4
Q

Acyclovir/ Acyclovir Sodium (Zovirax/ Zovira (Biovial)); Antiviral: Purine Nucleoside Analog

Rx; Preg Cat B

A

CNS: agitation, confusion, hallucinations, lethargy, tremors, seizures/coma (all systemic); CV: inflammation or phlebitis at infusion site, hypotension; DERM: burning/stinging at application site (topical), rash, hives, pruritus

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5
Q

Albuterol (Ventolin HFA)/ Salmeterol (Serevent Discus); Adrenergics: Bronchodilators

Rx; Preg Cat C

A

CNS: nervousness, restlessness, headache, insomnia; hyperactivity in children; CV: palpitations, hypertension, chest pain, angina, arrhythmias; ENDO: hyperglycemia; F/E: hyperkalemia; GI: N/V; NEURO: tremors; RESP: paradoxical bronchospasm c excessive use

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6
Q

Tamulosin (Flomax); Antiadrenergics

Rx; Preg Cat B

A

CNS: headache, dizziness, fatigue; CV: orthostatic hypotension; EENT: rhinitis, sinusitis; GI: nausea, abdominal pain, constipation, dyspepsia; GU: erectile dysfunction, diminished/retrograde ejaculation; RESP: pharyngitis, bronchitis

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7
Q

Alprazolam (Xanax)/ Lorazepam (Ativan); Antianxiety/Sedative-Hypnotics; Benzodiazepines

Rx; Preg Cat D

A

CNS: drowsiness, lethargy, dizziness, confusion, paradoxical excitement; DERM: rashes; EENT: blurry vision; GI: N/V/D, constipation, weight gain; OTHER: tolerance, physical and psychologic dependence

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8
Q

Amitriptyline (Generic); Tricyclic Antidepressants

Rx; Preg Cat C/D

A

CNS: suicidal ideations, lethargy, sedation, extrapyramidal reactions (nortriptyline); CV: arrythmias, hypotension, ECG changes; DERM: photosensitivity; EENT: blurry vision, dry eyes, dry mouth; ENDO: changes in blood glucose levels, gynecomastia; GI: constipation, hepatitis, paralytic ileum, unpleasant taste, ^ appetite and weight gain (amitriptyline); GU: urinary retention, decreased libido; HEM: blood dyscrasias

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9
Q

Amlodipine (Norvasc); Antihypertensive: Long Acting Calcium Channel Blocker

Rx; Preg Cat C

A

CNS: abnormal dreams, anxiety, dizziness, nervousness, peripheral neuropathy, hypoesthesia, tremor; CV: arrhythmias, bradycardia, chest pain, postural hypotension, peripheral schema; DERM: pruritus, rash; GI: N/V/D, anorexia, constipation, dry mouth, flatulence, gingival yperplasia; GU: micturition disorder, nocturia, sexual dysfunction; HEM: leukopenia, purpura, thrombocytopenia; MS: arthralgia, muscle cramps, myalgia; RESP: dyspnea, epistaxis; OTHER: abnormal vision, eye pain, hyperglycaemia, tinnitus, weight change

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10
Q

Amoxicillin (Amoxil, Trimox); Antibiotics: Penicillins (2nd Gen); Aminopenicillins

Rx; Preg Cat B

A

CNS: seizures c high doses; CV: edema; DERM: maculopapular rash, erythema multiforme, exfoliative dermatitis, urticaria; GI: glossitis, stomatitis, N/V/D, psuedomembranous colitis; HEM: anemia, thrombocytopenia, thrombocytopenic purpura, esoinophilia, leukopenia, agranulocytosis; HEP: ^ in serum AST; MS: athralgia; OTHER: fever, laryngeal edema, anaphylaxis, superinfection, serum sickness, crystalluria (overdose)

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11
Q

Aspirin (Acetylsalicyclic Acid) (Ascriptin, Bufferin, Easprin, Ecotrin, Empirin); Salicylate: Analgesic, Antiinflammatory, Antipyretic, Antiplatelet, NSAID

OTC/Rx for single ingredient formulation; Preg Cat D 1st trimester Rx Ciii; Preg Cat C 2nd and 3rd

A

CV: hypothrombinemia; DERM: skin rash, Stevens-Johnson syndrome, toxic epidermal necrolysis; EENT: tinnitus; GI: epigastric distress,N/V, abdominal pain, anorexia, GI bleeding; HEM: anemia, hemolysis, ^ bleeding time; HEP: hepatotxicity, ^ serum AST, ALT; OTHER: allergic reactions, incl. anaphylaxis and laryngeal edema

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12
Q

Atorvastatin (Lipitor)/ Pravastatin (Pravachol); HMG-CoA Reductase Inhibitors (also known as “statins”)

Rx; Preg Cat X

A

CNS: headache, dizziness, insomnia, weakness; CV: chest pain, peripheral edema; GI: altered taste, abdominal cramps, heartburn, N/V/D, constipation, flatus, drug-induced hepatitis, pancreatitis, ^ liver enzymes; MS: rhabdomyolisis, arthralgia, arthritis, myalgia, myositis; RESP: bronchitis; OTHER: hypersensitivity reactions

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13
Q

Azithromycin (Zinthromax); Antibiotics: Macrolide Antibiotics

Rx; Preg Cat B/C

A

CNS: dizziness, headache, somnolence, drowsiness, fatigue; CV: chest pain, palpitations, hypotension, prolonged Q-T interval (rare); DERM: Stevens-Johnson syndrome, toxic epidermal necrolysis, photosensitivity; GI: N/V/D, dyspepsia, flatulence, cholestatic jaundice, melena, pseudomembranous colitis; GU: monilia, nephritis, vaginitis; OTHER: angioedema

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14
Q

Lisinopril (Prinivil, Zestril); Antihypertensives, Angiotensin-Converting Enzyme Inhibitors (ACE-Is)

Rx; Preg Cat C during 1st trimester, D during 2nd/3rd trimester

A

CNS: headache, dizziness, mood changes, fatigue, insomnia; CV: hypotension, tachycardia, chest pain, palpitation, edema, MI (rare); DERM: flushing, rash, pruritus; ENDO: hyperuricemia; GI: taste disturbances, N/V/D, pain, dyspepsia, constipation; HEM: agranulocytosis, anemia, thrombocytosis, neutropenia (catopril only); MS: back pain, myalgia, muscle cramps; RESP: cough, dyspnea; OTHER: loss of taste, proteinuria, hyperkalemia, angioedema (enalapril and lisinopril most often)

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15
Q

Bupropion (Welbutrin); Antidepressant; Smoking Cessation Aid

Rx; Preg Cat B

A

CNS: headache, migraine, insomnia, dizziness, seizure disorders, neuropsychiatric disturbances, agitation, tremor, anxiety; CV: edema, ECG abnormalities, phlebitis (rare), tachycardia, cardiac arhythmias; DERM: rash, pruritus, dry skin, alopecia, hair colour change; EENT: visual and auditory disturbances; GI: dry mouth, N/V, constipation, anorexia, colitis (rare), bleeding; GU: nocturne, menstrual complaints, male sexual dysfunction; OTHER: weight loss, dyspnea, gynecomastia, fatigue, arthritis

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16
Q

Cepgalexin (Keflex); Antibiotics: Cephalosporins (1st Generation)

Rx; Preg Cat B

A

CNS: seizures in high doses; DERM: Stevens-Johnson syndrome, rashes, pruritus, urticaria, GI: psuedomembranous colitis, cramping, N/V/D; HEM: agranulocytosis, eosinophilia, hemolytic anemia, neutropenia, thromboytopenia; OTHER: pain at IM injection site, phlebitis at IV site, allergic reactions incl. anaphylaxis and serum sickness, superinfection

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17
Q

Celecoxib (Celebrex); Antiinflammatory: Cyclooxygenase-2 (COX-2) Inhibitor, NSAID

Rx; Preg Cat C

A

CNS: headache, dizziness, neuralgia; CV: peripheral edema, ^ hypertension, angina, tachycardia, MI (rare); DERM: alopecia, rash, photosensitivity (rare), exfoliative dermatitis (rare), Stevens-Johnson syndrome; GI: dyspepsia, abdominal pain, N/V/D, flatulence, GI bleeding, ulcers, taste changes; GU: infection, prostatic disorder, dysmenorrhea, dysuria, hematuria; HEM: thrombocytopenia (rare), anemia; RESP: pharyngitis, sinusitis, infection, dyspnea; OTHER: leg cramps, back pain, glaucoma, impaired vision, cataracts

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18
Q

Hydrochlorothiazide (HydroDIURIL); Diuretics (Thiazide); Antihypertensive

Rx; Preg Cat B

A

CNS: dizziness. vertigo, paresthesia, headache; CV: hypotension, hypercholesterolemia; DERM: purpura, urticaria, photosensitivity; EENT: blurred vision, xanthopsia; F/E: hypokalemia, hpercalcemia, hyperuricemia, hypochloremic alkalosis, hypomagnesemia, dehydration, hypovolemia; GI: anorexia, gastric irritation, N/V/D, jaundice, pancreatitis; HEM: agranulocytosis, aplastic anemia, leukopenia, thrombocytopenia; MS: fatigue, leg cramps; RESP: respiratory distress; OTHER: necrotizing angiitis

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19
Q

Famotidine (Pepcid)/ Ranitidine (Zantac); Histamine-2 Antagonists, Histamine-2 Blockers

Rx/OTC; Preg Cat B

A

CNS: confusion, dizziness, drowsiness, hallucinations, headache; CV: arrhythmias, vasculitis; ENDO: gynecomastia; GI: N/D, constipation, drug-induced hepatitis; GU: erectile dysfunction (cimetidine), decreased sperm count; HEM: agranulocytosis, aplastic anemia, anemia, neutropenia, thrombocytopenia

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20
Q

Ciprofloxacin (Cipro, Cipro XR, Proquin XR); Antibiotics: Fluoroquinolones

Rx; Preg Cat C

A

CNS: seizures, headache, insomnia, dizziness, acute psychoses, agitation, confusion, drowsiness; CV: arrhythmias (levofloxacin, moxifloxacin), prolonged Q-T interval, vasodilation; GI: N/D, abdominal pain, psuedomembranous colitis; DERM: Stevens-Johnson syndrome, rash, pruritus, urticaria; EENT: pharyngitis, rhinitis, tinitus, taste changes, visual disturbances; ENDO: hyper-/hypoglycemia; GU: vaginitis; MS: tendinitis, tendon rupture; OTHER: ^ liver function tests

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21
Q

Citalopram (Celexa); Antidepressants; SSRI

Rx; Preg Cat C

A

CNS: neuroleptic malignant syndrome, suicidal ideations, apathy, confusion, drowsiness, agitation, amnesia, anxiety; CV: postural hypotension, tachycardia; DERM: diaphoresis, photosensitivity, rash, pruritus; ENDO: weight loss/gain; F/E: hyponatremia; GI: abdominal pain, anorexia, N/D, dyspepsia, dry mouth, flatulence, altered taste, ^ saliva; GU: amenorrhea, dysmenorrhea, ejaculatory delay, erectile dysfunction, polyuria; MS: arthralgia, myalgia; NEURO: tremors, paresthesia; OTHER: serotonin syndrome, yawning, fever

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22
Q

Clonazepam (Klonopin); Benzodiazepine: Antiepileptic Drug

Rx Civ; Preg Cat D

A

CNS: drowsiness (50%), ataxia (30%), behaviour problems (25%), choreiform movements, coma, respiratory depression, hallucinations, psychosis, suicide attempts, dysarthria; CV: palpitations, ankle/facial edema; EENT: abnormal eye movement, diplopia; GI: anorexia, coated tongue, dry mouth, gastritis, nausea; HEM: anemia, leukopenia, thrombcytopenia, eosinophilia; HEP: hepatomegaly; MS: muscle weakness

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23
Q

Clonidine (Catapres. Catapres-TTS, Duraclon); Antihypertensive: a2 Agonist

Rx; Preg Cat C

A

CNS: drowsiness, sedation, headache, vivid dreams, anxiety, mental depression; CV: CHF, Raynaud’s phenomenon, ECG changes (usually ventricular trigeminy), AV block; DERM: rash, hives, alopecia, pruritus; EENT: nasal dryness, ocular irritation; GI: dry mouth, constipation, anorexia, vomiting, parotid pain; GU: urinary retention, impotence; OTHER: angioneurotic edema

24
Q

Codeine Sulfate; Opioid Analgesic

Rx Cii; Preg Cat C

A

CNS: sedation, lightheaded-ness, euphoria, dysphoria, tremors, disorientation, decrease seizure threshold; CV: hypotension, palpitations, flushing of face; DERM: pruritus, urticaria; EENT: miosis; GI: N/V, dry mouth, constipation, biliary tract spasm; GU: urine retention; RESP: respiratory depression

25
Q

Dalteparin (Fragmin); Anticoagulants: Low-Molecular-Weight Heparin Fragments

Rx; Preg Cat B

A

CNS: dizziness, headache, insomnia; CV: edema; DERM: ecchymosis, bullous eruptions, pruritus, rash, skin necrosis; GI: N/V, constipation, reversible ^ in liver function tests; HEM: bleeding, thrombocytopenia, anemia; OTHER: injection site hematomas (most common reaction), pain, anaphylactic reaction (rare), fever

26
Q

Diazepam (Valium); Antianxiety Drug; Sedative-Hypnotic: Benzodiazepine

Rx Civ; Preg Cat D

A

CNS: drowsiness, fatigue, ataxia, lethargy, headache, slurred speech, paradoxical excitation; CV: hypotension c IV use; DERM: rash; EENT: blurry vision; GI: N/V/D, constipation, weight gain; HEM: neutropenia (rare); RESPL respiratory depression; OTHER: pain c IM administration, phlebitis c IV administration, physical/psychological dependence, tolerance

27
Q

Diphenhydramine (Benadryl Allergy); Histamine-1 Antagonist (Histamine-1 Blocker)

Rx/ OTC; Preg Cat B

A

CNS: drowsiness, dizziness, headache, confusion, paradoxical excitement (children and older adults); DERM: photosensitivity, rash; EENT: blurry vision, tinnitus; GI: dry mouth, anorexia, nausea, constipation; GU: dysuria, frequency, urinary retention; RESP: chest tightness, thickened bronchial secretions, wheeling; OTHER: pain at injection site

28
Q

Esomeprazole (Nexium)/ Omeprazole (Losec, Prilosec)/ Pantoprazole (Protonix); Proton Pump Inhibitors

Rx; Preg Cat B

A

CNS: headache; CV: dry mouth, N/D, constipation, flatulence, abdominal pain; ENDO: hyperglycaemia (pantoprazole)

29
Q

Furosemide (Lasix); Loop Diuretic

Rx; Preg Cat C

A

CNS: dizziness, paresthesia, headache; CV: orthostatic hypotension; DERM: purpura, rash, urticaria, exfoliative dermatitis, erythemia, multiforme, photosensitivity; EENT: blurred vision, hearing loss, tinnitus; F/E: dehydration, hypocalcemia, hypochloremia, hypokalemia, hypomagnesemia, hyponatremia, metanolic alkalosis, hypovolemia; GI: anorexia, N/V/D, constipation, cramping, jaundice, pancreatitis; HEM: anemia, leukopenia, thrombocytopenia, aplastic anemia

30
Q

Gabapentin (Neurontin); Antiepileptic Drug; Analgesic Adjunct, Mood Stabilizer

Rx; Preg Cat C

A

CNS: suicidal ideations, anxiety, confusion, depression, sedation, difficulty concetrating (children), emotional lability, hostility, malaise, vertigo, weakness; CV: hypertension; GI: anorexia, gingivitis, flatulence, weight gain; MS: arthralgia; NEURO: ataxia, altered reflexes, hyperkinesia, paresthesias; OTHER: facial edema

31
Q

Heparin; Anticoagulant: High- Molecular-Weight Heparin; Antithrombotic

Rx; Preg Cat C

A

CV: vasospastic reactions may develop; HEM: hemorrhage, acute reversible thrombocytopenia (can appear up to several weeks after discontinuation of therapy); OTHER: decreased renal function, osteoporosis c long-term therapy; local irritation at subcut site

32
Q

Ibuprofen (Advil, Motrin); Antiinflammatory: Analgesic, Antipyretic, NSAID

Rx/ OTC; Preg Cat C/D

A

CNS: dizziness, headache, drowsiness; CV: edema, palpitations, CHF; DERM: rash, alopecia, pruritus, purpura, urticaria; EENT: tinnitus, decreased in hearing, blurred vision; GI: abdominal pain, N/V, constipation, stomatitis; GU: glomerular nephritis, hematuria, interstitial nephritis, nephrotic syndrome; HEM: agranulocytosis, aplastic anemia, hemolytic anemia; OTHER: thirst, eosinophilic pneumonia

33
Q

Ipratropium (Atrovent); Anticholinergics: Bronchodilators

Rx; Preg Cat B, C (combination products)

A

CNS: nervousness, dizziness, headache; CV: palpitations, tachycardia; EENT: glaucoma; GI: nausea, dry mouth, constipation; GU: urinary retention; RESP: paradoxical bronchospasm, cough, ^ in symptoms, bronchitis and URI (solution); OTHER: blurred vision (aerosol), chest and back pain (solution)

34
Q

Levothyroxine (Synthroid); Thyroid Replacement Hormone

Rx; Preg Cat A

A

Usually limited to OD; CNS: headache, insomnia, nervousness, tremors; CV: angina, cardiac arrhythmias, palpitations, tachycardia; GI: diarrhea; OTHER: intolerance to heat, sweating, weight loss

35
Q

Loratadine (Alavert, Claratin); Histamine-1 Antagonists; Histamine-1 Blockers

Rx/OTC; Preg Cat B (loratadine) C (fexofenadine)

A

CNS: drowsiness (rare), confusion, paradoxical excitation, fatigue; DERM: photosensitivity, rash; EEN: blurry vision, pharyngitis; ENDO: dysmenorrhea (fexofenadine); GI: dry mouth, GI upset; MET: weight gain; OTHER: anaphylaxis (desloratadine)

36
Q

Metformin (Glucophage, Fortamet); Oral Hypoglycemic: Biguanide

Rx; Preg Cat B

A

GI: anrexia, N/V/D, flatulence, transient metallic taste; HEM: decreased VB12 serum level, possible (rare) megaloblastic anemia; MET: lactic acidosis

37
Q

Methadone (Methadose, Dolophine); Opioid Analgesic

Rx Cii; Preg Cat C

A

CNS: headache, dizziness, confusion, sedation, dysphoria/euphoria, floating sensation, hallucinations, weird dreams; CV: hypotension, bradycardia, prolonged Q-T syndrome, torsades de pointes; DERM: flushing, sweating; EENT: blurred vision, diplopia, miosis; GI: N/V, constipation; GU: urinary retention; RESP: respiratory depression; OTHER: tolerance, physical and psychologic dependency

38
Q

Metoprolol Tartrate (Lopressor, Toprol XL); Antihypertensice: B-Adrenergic Blocker

Rx; Preg Cat C

A

CNS: tiredness, dizziness, depression, mental confusion; CV: bradycardia, palpitations, shortness of breath, cold extremities, CHF; DERM: pruritus, rash; GI: N/D, gastric pain, constipation, flatulence; OTHER: wheezing, Peyronie’s disease

39
Q

Metronidazole (Flagyl, Flagyl ER, Metrocream, MetroGel, MetroGel-Vaginal, MetroLotion); Antiamebic: Antibacterial

Rx; Preg Cat B

A

CNS: seizures, peripheral neuropathy, dizziness, incoordination, headache; CV: ECG T-wave flattening; DERM: Stevens-Johnson Syndrome, urticaria, erythematous rash, superinfection; EENT: nasal congestion; GI: anorexia, N/V/D, cramps, metallic taste; GU: dysuria, cystitis, polyuria, dark urine; HEM: leukopenia; NEURO: peripheral neuropathy

40
Q

Morphine Sulfate; Opium Alkaloid

Rx Cii; Preg Cat C

A

CNS: sedation, lightheaded-ness, euphoria, dysphoria, tremors, disorientation, decrease seizure threshold; CV: hypotension, palpitationsm flushing of face, phlebitis of IV site; DERM: pruritus, urticaria; EENT: mitosis; GI: N/V, dry mouth, constipation, biliary tract spasm; GU: urine retention; RESP: respiratory depression

41
Q

Naproxen (Naprelan); Analgesics; NSAIDs

Rx; Preg Cat B (1st Trimester)

A

CNS: dizziness, drowsiness, headahe; CV: edema, palpitations, tachycardia; DERM: sweating, pruritus, photosensitivity, rash, pseudoporphyria, Stevens-Johnson syndrome; EENT: abnormal vision, tinnitus; GI: drug-induced hepatitis, GI bleeding, N/V/D, constipation, flatulence, anorexia; GU: cystitis, hematuria, renal failure; HEM: blood dyscrasias, prolonged bleeding time; RESP: dyspnea; OTHER: allergic reactions, incl. anaphylaxis

42
Q

Oxycodone (Oxy IR, Oxycontin, Roxicodone)/ Oxycodone/Acetaminophen (Percocet); Opioid Analgesic

Rx Cii; Preg Cat C (oxycodone alone)

A

CNS: headache, sedation, confusion, dizziness, dysphoria, euphoria, floating feeling, hallucinations, unusual dreams; CV: orthostatic hypotension; DERM: flushing, diaphoresis; EENT: blurry vision, diplopia, miosis; GI: dry mouth, N/V, constipation; GU: urinary retention; RESP: respiratory depression; OTHER: physical/psychologic dependence

43
Q

Paroxetine HCL (Paxil, Paxil CR), mesylate (Pexeva); Antidepressant/ Antianxiety; SSRI

Rx; Preg Cat D

A

CNS: headache, anxiety, dizziness, agitation, amnesia, confusion, emotional lability, impaired concentration, syncope; CV: chest pain, hypertension, palpitations, edema, tachycardia, vasodilation; DERM: diaphoresis, photosensitivity, rash, pruritus; GI: taste disturbances, decreased appetite, N/V/D, constipation, dyspepsia, abdominal pain; GU: urinary frequency/ disorders, decreased libido, ejaculatory disturbances; MET: weight gain/loss; MS: back pain, myalgia, myopathy; NEURO: parenthesis, tremors; OTHER: fever, chills

44
Q

Penicillin V (Veebids)/ Penicillin G Benzathine (Bicillin L-A, Permapen)/ Penicillin G procaine (Wycillin); Antibiotic: Natural Penicillins

Rx; Preg Cat B

A

DERM: maculopapular rash, urticaria, exfoliative dermatitis; GI: N/V/D, epigastric distress, black hairy tongue; HEM: hemolytic anemia, leukopenia, thrombocytopenia; HEP: ^ serum AST, bilirubin; OTHER: Jarisch-Herxheimer reactions (arthralgia, chills, fever, headachem sore throat, sweating, altered BP), local pain at injection site, anaphylaxis, overgrowth of nonsusceptible oganisms

45
Q

Prednisone (Steraped)/ MethylPREDNISolone (Solu-Medrol); Immunosuppressants: Systemic Corticosteroids

Rx; Preg Cat C

A

CNS: headache, depression, euphoria, restlessness, personality changes; CV: hypertension; EENT: cataracts, ^ IOP (children only); ENDO: hyperglycaemia, adrenal suppression; F/E: fluid retention; c long-term high dosages, hypokalemia, hypokalemic alkalosis; GI: peptic ulceration, anorexia, N/V; HEM: thromboembolism, thrombophlebitis; MET: weight gain; MS: muscle wasting, osteoporosis, avascular necrosis of joints, muscle pain; OTHER: cushingoid appearance (moon face), buffalo hump), ^ susceptibility for infection

46
Q

Quetiapine (Seroquel); Antipsychotic: Neuroleptic

Rx; Preg Cat C

A

CNS: dizziness, postural hypotension, headache somnolence, extrapyramidal symptoms; CV: tachycardia, palpitations, peripheral edema, vasodilation, ECG changes; EENT: pharyngitis, visual disturbances, tinnitus; GI: dry mouth, dyspepsia, constipation, anorexia, taste disorders; HEM: leukopenia, thrombocytopenia (rare); OTHER: sweating, dysmenorrhea, hypothyroidism, weight gain

47
Q

Risperidone (Risperdal); Antipsychotic, Mood Stabilizer

Rx; Preg Cat C

A

CNS: extrapyramidal symptoms, headache, insomnia, dizziness, agitation, anxiety, somnolence, aggressive behaviour, neuroleptic malignant syndrome, tardive dyskinesia; CV: pro arrhythmic effects, orthostatic hypotension, prolonged Q-T interval; DERM: rash, photosensitivity, urticaria; EENT: cataract, conjunctivitis, tinnitus, tonsillitis; GI: N/V, constipation, dyspepsia; GU: female/male sexual dysfunction; RESP: coughing, dyspnea, rhinitis; OTHER: ^ salivation, back pain, fever

48
Q

Sitagliptin (Januvia); Antidiabetics: DPP-4 Inhibitors

Rx; Preg Cat B

A

CNS: headache; CV: facial and peripheral edema; ENDO: decreased hypoglycemia; GI: abdominal pain, gastroenteritis, vomiting; HEM: decreased lymphocytes; RESP: nasopharyngitis, sinusitis, URTIs; OTHER: bone fractures, UTIs

49
Q

Sertraline (Zoloft); Antidepressant; SSRI

Rx; Preg Cat C

A

CNS: neuroleptic malignant syndrome, suicidal ideations, dizziness, drowsiness, fatigue, headache, insomnia, agitation, anxiety, confusion, emotional lability, impaired concentration, mania, nervousness, weakness, yawning; CV: palpitations, chest pain; DERM: sweating, rash, hot flashes; F/E: hyponatremia; GI: dry mouth, ate red taste, thirst, abdominal pain, anorexia, constipation, dyspepsia, flatulence, vomiting, ^ appetite; GU: sexual dysfunction, menstrual disorders, urinary frequency/disorders; MS: back pain, myalgia; NEURO: tremors, hypoertonia, hypoesthesia, paresthesia, twitching; OTHER: serotonin syndrome, fever

50
Q

Spironolactone (Aldactone); Diuretic: Aldosterone Antagonist, Potassium-Sparin Diuretic

Rx; Preg Cat D

A

CNS: drowsiness, headache, lethargy, confusion; DERM: urticaria, drug fever, skin rash, hirsutism; GI: cramps, diarrhea; GU: amenorrhea, irregular menses, postmenopausal bleeding, impotence; MET: hyperkalemia; OTHER: gynecomastia, carcinoma of breast (no cause-effect relationship established), deepening of voice

51
Q

Tramadol (Ultram, Ultram ER, Ryzolt); Centrally-Acting Nonopioid Analgesic

Rx; Preg Cat C

A

CNS: seizures, headache, dizziness, somnolence, anxiety, confusion, coordination disturbance, euphoria, malaise, nervousness, sleep disorder; CV: vasodilation; DERM: pruritus, sweating; EENT: visual disturbances; GI: anorexia, dry mouth, abdominal pain, constipation, V/D, flatulence, dyspepsia; NEURO: hypertonia; OTHER: psychologic or physical dependence

52
Q

Trazodone; Antidepressant

Rx; Preg Cat C

A

CNS: suicidal ideations, drowsiness, confusion, dizziness, fatigue, nightmares, slurred speech, syncope, weakness; CV: hypotension, arrhythmias, chest pain, paplitations, hypertension, prolonged Q-T interval, tachycardia; EENT: blurry vision, tinnitus; GI: dry mouth, altered taste, excessive salivation, flatulence, N/V, constipation; GU: hematuria, erectile dysfunction, priapism, urinary frequency; MS: myalgia; NEURO: tremors

53
Q

Venlafaxine (Effexor, Effexor XR); Antidepressant; Selective Serotonin/ Norepinephrine Reuptake Inhibitor

Rx; Preg Cat C

A

CNS: dizziness, somnolence, headache, tremor, attention disturbances, anxiety, insomnia, irritability, abnormal dreams; CV: chest pain, palpitations, ^ BP; DERM: hyperhidrosis, rash; EENT: blurry vision, mydriasis, tinnitus, dysgeusia; GI: decreased apetite, dry mouth, N/V/D, constipation, weight loss; GU: decreased libido, erectile dysfunction, anorgasmia; NEURO: parenthesis; RESP: yawning; OTHER: fatigue, chills, feeling jittery, hot flashes

54
Q

Verapamil (Calan, Calan SR, Covera HS, Isoptin SR, Varelan, Varelan PM, Generic); Antihypertensive: Calcium Channel Blocker

Rx; Preg Cat C

A

CNS: dizziness, headache, insomnia, confusion, abnormal dreams, anxiety, nervousness, psychiatric disturbances; CV: hypotension, palpitations, peripheral edema, AV block, bradycardia, CHF; DERM: alopecia; EENT: blurred vision; GI: anorexia, N/V, constipation, hyperglcycemia; GU: gynecomastia, spotty menstruation; MS: muscle cramps

55
Q

Warfarin Sodium (Coumadin); Coumarin Anticoagulant

Rx; Preg Cat X

A

DERM: dermatitis, urticaria, alopecia; GI/GU: hemorrhage; HEM: agranulocytosis, leukopenia, anemia; HEP: hepatitis, jaundice; OTHER: fever