SIADH Flashcards
1
Q
What is SIADH?
A
Increased release of ADH from the posterior pituitary
2
Q
What is the impact of too much ADH?
A
Water reabsorption from the urine is increased (in the collecting ducts of the kidneys)- this causes hyponatraemia
3
Q
What are the two potential sources of excess ADH?
A
Increased production by the posteior pituitary
Ecoptic ADH, most commonly from small cell lung cancer
4
Q
What is serum and urine osmolality like in SIADH?
A
Low serum osmolality
High urine osmolality
5
Q
What is the presentation of SIADH?
A
Headache
Fatigue
Muscle cramps
Confusion
6
Q
What are the possible causes of SIADH?
A
Post-op after major surgery
Lung infection
Brain pathologies - head injury, stroke, meningitis
Medications - SSRIs, carbamazepine
Small cell lung cancer
HIV
7
Q
A
