Interstitial Lung Disease Flashcards
What is interstitial lung disease?
A group of conditions that cause inflammation and fibrosis of the lung parenchyma
What conditions are under interstitial lung disease?
Idiopathic pulmonary fibrosis
Secondary pulmonary fibrosis
Hypersensitivity pneumonitis
Asbestosis
What is the presentation of interstitial lung disease?
Shortness of breath on exertion
Dry cough
fatigue
What signs do patients with idiopathic pulmonary fibrosis have on examination?
Bibasal fine end-inspiratory crackles
Finger clubbing
How is IPF diagnosed?
Spirometry
Reduced transfer factor (TLCO)
CXR
CT
What spirometry results are seen in IPF?
Restrictive picture
- FEV1 normal/decreased
- FVC decreased
- FEV1:FVC increased
What is the investigation of choice for diagnosis of IPF?
CT
What is the management of IPF?
Pulmonary rehabilitation
Smoking cessation
Home oxygen (if hypoxic)
Pneumococcal and flu vaccines
Advanced care planning
Which medications can slow the progression of IPF?
Pirfenidone
Nintedanib