SI Flashcards

1
Q

three sections

A

duodenum, jejunum, ileum

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2
Q

duodenum

A

curves round the head of the pancreas, secretions from the gall bladder and pancreas merge into the hepatopancreatico-ampulla which enter the duodenal papilla. This is guarded by a smooth muscle rung - hepatic-pancreatic sphincter

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3
Q

ileum

A

terminal section, ends at the ileoceacal valves, controlling flow, preventing back flow

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4
Q

how is it attached

A

with the stomach at the pyloric sphincter becomes the LI via the ileocaecal valves

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5
Q

what processes occur

A

chemical digestion is completed
absorption occurs

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6
Q

what absorb fat

A

lacteals, transporting them along lymph vessels to the thoracic duct where it enters circulation

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7
Q

describe the peritoneum layer

A

double layer of peritoneum - mesentery attaches to the jejunum and the ileum to the posterior abdominal wall. The attachment creates a fan shape
the large blood vessels and nerves lie on the posterior abdominal wall and branches to the SI pass between the two mesentry layers

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8
Q

mucosal layer

A

large surface area, with circular folds, villi and microvilli, the circular folds are permanent so don’t smooth out when distended, promoting the mixing of chyme
villi composed of columnar epithelium with microvilli on their free birder throughout the enterocytes are goblet cells interspersed.
capillary network is formed and central lymph capillary

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9
Q

where does the final stages of digestion take place

A

in the enterocytes before entering the capillaries

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10
Q

what are the intestinal glands

A

simple tubular glands which are found below the villi, the epithelium migrate up to form the villi walls replacing the cells at the tips which have been rubbed off by the intestinal contents
during migration the epithelial cells produce digestive enzymes which lodge themselves in the microvilli with the intestinal juice.

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11
Q

where are LN found

A

irregular intervals
solitary lymphoid follicles, are small
at the distal end there is aggregated lymphatic follicles (20 or 30 larger nodes- PEYERS PATCHES)
packed defensive cells which neutralise ingested antigens

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12
Q

functions

A

peristalsis; para-sympathetic increases waves
intestinal juice secretions via PS
chemical digestion is completed in the enterocytes
protection against microbes by solitary and aggregated follicles
secretion of cholecystokinin and secretin
absorption of nutrients

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13
Q

pancreatic juice

A

secreted by the endocrine pancreas, enters at the duodenal papilla
slightly alkaline due to the bicarbonate ions
pancreatic lipase and amylase optimum is 8
stimulated by secretin and CCK
acid chyme stimulates hormone production

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14
Q

PJ consists of

A

water
mineral salts
enzymes: lipas, amylase, nuclease
inactive enzyme precursors: trypsinogen, chymotrypsinogen

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15
Q

protein digestion

A

trypsinogen and chymotrypsinogen are activated by enterokinase (in microvilli) coverting them into active form, which breaks down proteins to AA

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16
Q

carb digestion

A

pancreatic amylase converts all remaining polysaccharides into disaccharides

17
Q

lipid digestion

A

bile salts and lipase increases SA

18
Q

what do intestinal secretions have

A

sucrase, maltase and lactase completing carb digestion

19
Q

what is the main stimulus for IJ

A

mechanical stimulation of the glands by chyme is the main stimulus, however secretin may be involved

20
Q

what does vitamin-12 combine with

A

intrinsic factor from the stomach, actively absorbed in the terminal ileum

21
Q

bile

A

secreted by live: passes from hepatic duct along the cystic duct to gall bladder, when hepatopancreatico sphincter is closed

22
Q

bile consists of

A

bile salts (emulsify fats)
cholesterol
water
mineral salts
mucus
bile pigments (bilirubicin)

cholesterol and fatty acids become soluble for absorption