Short Stature

Question 1

What is familial short stature

Answer 1

When genetic factors affect growth rate

Question 2

What is Constitutional growth delay?

Answer 2

Slow growth velocity but they catch up when they grow up

Question 3

What is a reason for Constitutional growth delay?

Answer 3

Malnutrition during gestational period

Question 4

How does an endocrine disorder lead to short stature?

Answer 4

Growth hormone deficiency, which leads to no IGF-1, which is stimulated at the liver by the GH

Question 5

What is precocious puberty?

Answer 5

Puberty before menstruation at the age of 8, and sexual development in males before 9

Question 6

What is Disproportionate short stature linked to?

Answer 6

Genetic mutation

Question 7

How is short stature diagnosed?

Answer 7

Measuring height, tracking puberty, checking family history

Question 8

What lab tests do we do?

Answer 8

IGF-1 levels

Question 9

What imaging do we do?

Answer 9

X-rays to correlate bone age with chronological age

Question 10

How do we treat short stature caused by an underlying hormone deficiency?

Answer 10

Via gondotrophin releasing hormone analogs