Shock - Full summary Flashcards
What is meant by shock?
An abnormality of the circulatory system, resulting in inadequate tissue perfusion and oxygenation
How can shock cause cellular failure?
Inadequate tissue perfusion can lead to anaerobic metabolism, which results in accumulation of metabolic waste, resulting in cellular failure
What 2 factors does adequate tissue perfusion depend on?
Adequate Mean arterial pressure (MAP)
Adequate Cardiac Output (CO)
What are the 4 main classes of shock?
Hypovolaemic shock
Cardiogenic shock
Obstructive shock
Distributive shock
What is hypovolaemic shock?
Shock caused by a loss of blood volume
What are the 2 types of hypovolaemic shock?
Haemorrhagic shock
Non-Haemorrhagic shock
What causes haemorrhagic shock?
This is a decrease in blood volume caused by direct loss of blood, either by trauma, surgery or GI haemorrhage
What causes non-hemorrhagic shock?
This is shock caused by a loss of fluid in the body by processes such as vomiting, diarrhoea or excessive sweating
Describe the pathophysiology of hypovolaemic shock
Loss of blood volume
Decreased venous return
Decreased end diastolic volume
Decreased stroke volume (Frank-Starling)
Decreased cardiac output and MAP
Inadequate tissue perfusion
Up until what percentage of blood loss can compensatory mechanisms maintain blood pressure?
30%
How do compensatory mechanisms increase blood pressure?
Decrease in blood volume causes a decrease in blood pressure
Baroreceptors detect this and stimulate an increase in SVR and heart rate
What are some common symptoms of hypovolaemic shock?
Cold peripheries
Tachycardia
Small volume pulse
What is meant by Class I haemorrhagic shock?
≤15% blood loss (750mL) and normal BP
What is meant by class II haemorrhagic shock?
15-30% blood loss (750-1500mL) and normal BP
What is meant by class III haemorrhagic shock?
30-40% blood loss (1500-2000mL) and low BP