Shock Flashcards
Anoxia
total depletion or absence of oxygen
Hypoxemia
low oxygen in the blood
Hypoxia
abnormally low oxygen content in any tissue or organ
Inability to correct and reverse shock results in
- increasing oxygen debt
- acidosis
- organ system dysfunction
- death
What happens at the cellular level during shock?
- impaired oxygen use
- impaired glucose use
- buildup of metabolic end products
How does anaerobic metabolism lead to cell death?
a. inadequate energy production»_space; metabolic failure
b. lactic acid production»_space; metabolic acidosis
Gluconeogenesis
formation of glucose in the liver from non-carbohydrate carbon substrates
Systemic Effects of Shock
- Lungs (impaired gas exchange - ARDS, respiratory failure)
- Heart (myocardial deterioration)
- Blood (hypercoagulable)
- Neuroendocrine (SNS activation and increased ACTH)
- Immune, GI and renal systems
Acute Respiratory Distress Syndrome
sudden life-threatening lung failure
inflammation of alveoli causing them to fill with liquid and collapse. gas exchange cease and body becomes starved of oxygen
Disseminated Intravascular Coagulation (DIC)
Multiple thrombi or emboli in microvascular circulation
Lab findings:
a. thrombocytopenia
b. prolonged PT, aPTT, thrombin
c. decreased fibrinogen
d. elevated d-dimers
Adequate circulating volume is dependent on which 3 interrelated components of the CV system?
a. heart
b. vascular tone
c. blood volume
Name 4 compensatory mechanisms of shock
- baroreceptors
- chemoreceptors
- circulating vasoconstrictors
- kidney and the RAAS
Clinical manifestations of shock (CHORD ITEM)
C - cardiac output decreased H - hypotension O - oliguria R - rapid, shallow breathing D - drowsiness, confusion, decreased LOC
I - irritability
T - tachycardia
E - extremities cool, clammy skin
M - multi-organ damage
Types of Shock
a. Hypovolemic
b. Obstructive
c. Cardiogenic
d. Vasogenic (distributive)
Which type of shock is characterized by the following?
High SVR Poor skin turgor Thirst Oliguria Rapid HR Elevated RR Altered LOC Low BP
Hypovolemic Shock