Shigella Flashcards

1
Q

What is Shigella and how is it different to the other bacteria in this theme?

A

Slides 2-4

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2
Q

What determines the pathogenicity of Shigella?

A

Slide 6

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3
Q

What is the pathogenesis of Shigella? How does it invade cells?

A

T3SS

Slides 12-16

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4
Q

Discuss the T3SS system in Shigella and how it is activated/regulated.

A

Slides 17-20

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5
Q

How do avirulent colonies of Shigella differ from virulent colonies and why?

A

virulence is a trade-off

Slides 22-24

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6
Q

Discuss the toxin:antitoxin system in Shigella.

A

Slides 25-28

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7
Q

Give an example of how avirulence is caused.

A

Slide 29

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8
Q

What is the difference between S. flexneri and S. sonnei? How can this difference be exploited?

A

Slides 30-32

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9
Q

Discuss the AMR of Shigella.

A

Slides 34-37

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