SGLT-2 Renal Dosing

Question 1

SGLT given at > 60 eGFR

Answer 1

Canagliflozin : 100 mg with a max of 300 mg. Ertugliflozin: 5mg with a max of 15mg

Question 2

What drugs can be given at 30 to 60 eGFR

Answer 2

Canagliflozin at 100 mg max a day. Do not start Ertugliflozin, if on therapy, stop if EGFR is too low

Question 3

What drug can be given for eGFR of 31 to 60

Answer 3

Empagliflozin at 10 mg/ day with max of 25mg

Question 4

What drug can be given for 25 to 60 eGFR

Answer 4

Dapagliflozin at 5 mg/day and a max of 10 mg

Question 5

What drugs can be given for < 30 eGFR

Answer 5

You can’t start Canagliflozin but if on it, only use 100 mg daily if albumin > 300.

Question 6

What drug can you start for < 25 eGFR

Answer 6

You cannot start dapagliflozin, but if on there or, continue and monitor