Sexually Transmitted Diseases Flashcards
Syphillus Chlamydia Gonococcal infections Herpes HPV
1
Q
Primary and Secondary Syphilis
A
within one work day
2
Q
All other stages of Syphilis
A
one week
3
Q
Chlamydia
A
one week
4
Q
Gonococcal infections
A
one week
5
Q
Herpes
A
nope
6
Q
HPV
A
nope
7
Q
What causes syphilis?
A
Treponema pallidum
8
Q
“O” of TORCH?
A
Syphilis
9
Q
How is Syphilis transmitted?
A
Sexually acquired
Vertical transmission
10
Q
What is the longest progression of syphilis?
A
late (tertiary) syphilis
11
Q
Where is the classic chancre of syphilis seen?
A
primary
12
Q
What develops at the site of inoculation for syphilis?
A
painless papule
13
Q
What are 3 risk factors of Syphilis?
A
- HIV infection
- Combination methamphetamine and sildenafil use
- Having acquired recent sexual partners from the internet
14
Q
What are the 4 Stages of syphilis?
A
- Primary
- Secondary
- Latent
- Tertiary
15
Q
What is one to two centimeter ulcer with a raised, indurated margin called?
A
chancre
16
Q
How long does it take the chancre to heal spontaneously?
A
3-6 wks
17
Q
Where is a wide variety of symptoms seen in syphilis?
A
Secondary syphilis
18
Q
What is the most characteristic finding in secondary syphilis?
A
Rash (not vesicles)
19
Q
Where stage of syphilis is condyloma lata found?
A
Secondary syphilis
20
Q
What are Condyloma lata?
A
weeping papules
21
Q
T/F There are signs and symptoms in Latent Syphilis?
A
False
22
Q
When dos early latent occur?
A
1st year after infection
23
Q
When is syphilis non-infectious to sex partners?
A
Late latent
24
Q
When is syphilis infectious to sex partners?
A
Early latent
25
When is the transmission to fetus still possible although non-infectious to sex partners?
Late latent
26
What are 3 symptoms that can occur in Late syphilis?
- Gummatous
- Cardiovascular
- Neurosyphilis
27
Gummatous syphilis occurs where?
Anywhere (skin, bones, or internal organs)
28
What gummas?
heaped up granulomatous lesions
29
What cardiovascular structures are infected by syphilis?
ascending thoracic aorta
30
What cardiovascular problems does syphilis create?
Dilated aorta
| Aortic valve regurgitation
31
Syphilis on the central nervous system
Neurosyphilis
32
Argyll Robertson pupils
"Prostitution pupils" (accommodates but don't react)
33
Where s Tabes dorsalis found?
Neurosyphilis syphilis
34
What are the two nontreponemal screening tests for syphilis?
- Venereal Disease Research Laboratory (VDRL)
| - Rapid Plasma Reagin (RPR)
35
What are the two treponemal confirming tests for syphilis?
- Fluorescent treponemal antibody absorption (FTA-ABS)
| - Microhemagglutination test for antibodies to T. pallidum (MHA-TP)
36
To visualize syphilis spirochete
Darkfield microscopy
37
What is the treatment for syphilis?
Penicillin
38
What cures syphilis?
penicillin
39
Used as a alternative for penicillin drug allergy for syphilis
azithromycin
40
What is Jarisch Herxheimer reaction?
massive destruction of spirochetes in early syphilis. Reaction resolves within 24 hrs
41
What is found in tropical/ subtropical regions
Chlamydia Lymphogranuloma Venereum
42
What is predominately a disease of Lymphatic tissue?
Chlamydia Lymphogranuloma Venereum
43
What is seen primarily in lymphogranuloma venereum
genital ulcer/ mucosal inflammatory reaction
44
What is seen in secondary stage lymphogranuloma venereum?
painful inguinal buboes
45
How do you diagnosis lymphogranuloma venereum
PCR for LGV-specific DNA
46
What is the FIRST treatment for LGV
Doxycycline
47
What is the SECOND treatment for LGV in allergic or pregnant pts
erythromycin
48
What is the major cause of nongonoccal urethritis and cervicitis?
Chlamydia
49
What is Chlamydia often co-infected with?
gonococci
50
When chlamydia is the only infection its.....
asymptomatic
51
What is the most infected site in women?
cervix
52
What is the most infected site in men?
urethra
53
What is the most common presenting symptom of chlamydia in women?
Cervicitis
54
What is the most common presenting symptom of chlamydia in men?
Urethritis
55
What are two symptoms found in both men and women?
- Conjunctivitis
| - Pharyngitis
56
How do you diagnosis Chlamydia?
Nucleic acid amplification test (NAAT)
57
How do you distinguish the diagnosis of Chlamydia from gonorrhea?
urethritis or cervicitis MINUS gram neg diplococci
58
How do you treat Chlamydia?
Azithromycin or doxycycline
59
Who is at highest risk of gonorrhoeae infection?
black men and black women
60
What is the most common symptom seen in women with gonorrhea?
Cervicitis and urethritis
61
What is the most common symptom seen in men with gonorrhea?
urethritis
62
How do you diagnosis gonorrhea?
Nucleic acid amplification tests (NAATs)
63
How do you treat gonorrhea?
Ceftriaxone PLUS azithromycin
64
What med is no longer acceptable in gonorrhea treatment?
Fluoroquinolones
65
What is the strongest predictor of HSV infection?
lifetime number of sex partners
66
What type of herpes is often oral?
HSV-1
67
What type of herpes is often genital?
HSV-2
68
T/F can you get Herpes from someone without lesion?
YES YES YES
69
What is the most common presentation of herpes?
oral lesion
70
Who is more prone to Herpetic whitlow?
Dentists
| Children
71
Who gets herpes gladiatorum?
wrestlers
72
What is associated with high morbidity and mortality in Herpes?
encephalitis
73
How is herpes simplex diagnosed
based on the appearance of the lesion
74
What is the GOLD STANDARD for diagnosing herpes?
Viral culture
75
What has replaced the GOLD STANDARD for diagnosing herpes?
PCR
76
What can differentiate type 1 from type 2 herpes?
Serology
77
What is the treatment for the first episode of herpes?
Acyclovir
78
What is the treatment for the recurrent episode of herpes?
Acyclovir
79
What are two topical treatment options for oral herpes?
Penciclovir
| Docosanol
80
A patient has ocular herpes what should be done??
URGENT referral to Ophthalmologist
81
What is the DOC for acyclovir resistance in immunocompromised persons with systemic HIV?
Foscarnet
82
What is the most common viral sexually transmitted disease in U.S.?
Condylomata Acuminata
83
What causes condylomata?
HPV
84
Condylomata acuminata is at increased risk for what?
anogenital (cervical cancer)
| head and neck cancers
85
How many types can cause malignant change?
35 types
86
Which types are associated with high grade squamous intraepithelial neoplasia?
16, 18, 31, 33, 35
87
What are two odd risk factors for condylomata acuminata?
Cigarette smoking
| Radiation therapy
88
What is the most common presentation in condylomata?
WART
89
How is condylomata diagnosed?
clinical presentation, serologic testing for syphillis
90
What is the treatment for Condylomata?
Podophyllin and podofilox
Imiquimod
Sinecatechines
91
How do you prevent Condylomata?
Gardasil- 9 vaccine
