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Infectious Disease > Sexually Transmitted Diseases > Flashcards

Sexually Transmitted Diseases Flashcards

Syphillus Chlamydia Gonococcal infections Herpes HPV

1
Q

Primary and Secondary Syphilis

A

within one work day

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2
Q

All other stages of Syphilis

A

one week

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3
Q

Chlamydia

A

one week

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4
Q

Gonococcal infections

A

one week

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5
Q

Herpes

A

nope

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6
Q

HPV

A

nope

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7
Q

What causes syphilis?

A

Treponema pallidum

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8
Q

“O” of TORCH?

A

Syphilis

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9
Q

How is Syphilis transmitted?

A

Sexually acquired

Vertical transmission

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10
Q

What is the longest progression of syphilis?

A

late (tertiary) syphilis

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11
Q

Where is the classic chancre of syphilis seen?

A

primary

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12
Q

What develops at the site of inoculation for syphilis?

A

painless papule

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13
Q

What are 3 risk factors of Syphilis?

A
  • HIV infection
  • Combination methamphetamine and sildenafil use
  • Having acquired recent sexual partners from the internet
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14
Q

What are the 4 Stages of syphilis?

A
  • Primary
  • Secondary
  • Latent
  • Tertiary
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15
Q

What is one to two centimeter ulcer with a raised, indurated margin called?

A

chancre

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16
Q

How long does it take the chancre to heal spontaneously?

A

3-6 wks

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17
Q

Where is a wide variety of symptoms seen in syphilis?

A

Secondary syphilis

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18
Q

What is the most characteristic finding in secondary syphilis?

A

Rash (not vesicles)

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19
Q

Where stage of syphilis is condyloma lata found?

A

Secondary syphilis

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20
Q

What are Condyloma lata?

A

weeping papules

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21
Q

T/F There are signs and symptoms in Latent Syphilis?

A

False

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22
Q

When dos early latent occur?

A

1st year after infection

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23
Q

When is syphilis non-infectious to sex partners?

A

Late latent

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24
Q

When is syphilis infectious to sex partners?

A

Early latent

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25
Q

When is the transmission to fetus still possible although non-infectious to sex partners?

A

Late latent

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26
Q

What are 3 symptoms that can occur in Late syphilis?

A
  • Gummatous
  • Cardiovascular
  • Neurosyphilis
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27
Q

Gummatous syphilis occurs where?

A

Anywhere (skin, bones, or internal organs)

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28
Q

What gummas?

A

heaped up granulomatous lesions

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29
Q

What cardiovascular structures are infected by syphilis?

A

ascending thoracic aorta

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30
Q

What cardiovascular problems does syphilis create?

A

Dilated aorta

Aortic valve regurgitation

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31
Q

Syphilis on the central nervous system

A

Neurosyphilis

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32
Q

Argyll Robertson pupils

A

“Prostitution pupils” (accommodates but don’t react)

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33
Q

Where s Tabes dorsalis found?

A

Neurosyphilis syphilis

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34
Q

What are the two nontreponemal screening tests for syphilis?

A
  • Venereal Disease Research Laboratory (VDRL)

- Rapid Plasma Reagin (RPR)

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35
Q

What are the two treponemal confirming tests for syphilis?

A
  • Fluorescent treponemal antibody absorption (FTA-ABS)

- Microhemagglutination test for antibodies to T. pallidum (MHA-TP)

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36
Q

To visualize syphilis spirochete

A

Darkfield microscopy

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37
Q

What is the treatment for syphilis?

A

Penicillin

38
Q

What cures syphilis?

A

penicillin

39
Q

Used as a alternative for penicillin drug allergy for syphilis

A

azithromycin

40
Q

What is Jarisch Herxheimer reaction?

A

massive destruction of spirochetes in early syphilis. Reaction resolves within 24 hrs

41
Q

What is found in tropical/ subtropical regions

A

Chlamydia Lymphogranuloma Venereum

42
Q

What is predominately a disease of Lymphatic tissue?

A

Chlamydia Lymphogranuloma Venereum

43
Q

What is seen primarily in lymphogranuloma venereum

A

genital ulcer/ mucosal inflammatory reaction

44
Q

What is seen in secondary stage lymphogranuloma venereum?

A

painful inguinal buboes

45
Q

How do you diagnosis lymphogranuloma venereum

A

PCR for LGV-specific DNA

46
Q

What is the FIRST treatment for LGV

A

Doxycycline

47
Q

What is the SECOND treatment for LGV in allergic or pregnant pts

A

erythromycin

48
Q

What is the major cause of nongonoccal urethritis and cervicitis?

A

Chlamydia

49
Q

What is Chlamydia often co-infected with?

A

gonococci

50
Q

When chlamydia is the only infection its…..

A

asymptomatic

51
Q

What is the most infected site in women?

A

cervix

52
Q

What is the most infected site in men?

A

urethra

53
Q

What is the most common presenting symptom of chlamydia in women?

A

Cervicitis

54
Q

What is the most common presenting symptom of chlamydia in men?

A

Urethritis

55
Q

What are two symptoms found in both men and women?

A
  • Conjunctivitis

- Pharyngitis

56
Q

How do you diagnosis Chlamydia?

A

Nucleic acid amplification test (NAAT)

57
Q

How do you distinguish the diagnosis of Chlamydia from gonorrhea?

A

urethritis or cervicitis MINUS gram neg diplococci

58
Q

How do you treat Chlamydia?

A

Azithromycin or doxycycline

59
Q

Who is at highest risk of gonorrhoeae infection?

A

black men and black women

60
Q

What is the most common symptom seen in women with gonorrhea?

A

Cervicitis and urethritis

61
Q

What is the most common symptom seen in men with gonorrhea?

A

urethritis

62
Q

How do you diagnosis gonorrhea?

A

Nucleic acid amplification tests (NAATs)

63
Q

How do you treat gonorrhea?

A

Ceftriaxone PLUS azithromycin

64
Q

What med is no longer acceptable in gonorrhea treatment?

A

Fluoroquinolones

65
Q

What is the strongest predictor of HSV infection?

A

lifetime number of sex partners

66
Q

What type of herpes is often oral?

A

HSV-1

67
Q

What type of herpes is often genital?

A

HSV-2

68
Q

T/F can you get Herpes from someone without lesion?

A

YES YES YES

69
Q

What is the most common presentation of herpes?

A

oral lesion

70
Q

Who is more prone to Herpetic whitlow?

A

Dentists

Children

71
Q

Who gets herpes gladiatorum?

A

wrestlers

72
Q

What is associated with high morbidity and mortality in Herpes?

A

encephalitis

73
Q

How is herpes simplex diagnosed

A

based on the appearance of the lesion

74
Q

What is the GOLD STANDARD for diagnosing herpes?

A

Viral culture

75
Q

What has replaced the GOLD STANDARD for diagnosing herpes?

A

PCR

76
Q

What can differentiate type 1 from type 2 herpes?

A

Serology

77
Q

What is the treatment for the first episode of herpes?

A

Acyclovir

78
Q

What is the treatment for the recurrent episode of herpes?

A

Acyclovir

79
Q

What are two topical treatment options for oral herpes?

A

Penciclovir

Docosanol

80
Q

A patient has ocular herpes what should be done??

A

URGENT referral to Ophthalmologist

81
Q

What is the DOC for acyclovir resistance in immunocompromised persons with systemic HIV?

A

Foscarnet

82
Q

What is the most common viral sexually transmitted disease in U.S.?

A

Condylomata Acuminata

83
Q

What causes condylomata?

A

HPV

84
Q

Condylomata acuminata is at increased risk for what?

A

anogenital (cervical cancer)

head and neck cancers

85
Q

How many types can cause malignant change?

A

35 types

86
Q

Which types are associated with high grade squamous intraepithelial neoplasia?

A

16, 18, 31, 33, 35

87
Q

What are two odd risk factors for condylomata acuminata?

A

Cigarette smoking

Radiation therapy

88
Q

What is the most common presentation in condylomata?

A

WART

89
Q

How is condylomata diagnosed?

A

clinical presentation, serologic testing for syphillis

90
Q

What is the treatment for Condylomata?

A

Podophyllin and podofilox
Imiquimod
Sinecatechines

91
Q

How do you prevent Condylomata?

A

Gardasil- 9 vaccine

Infectious Disease (6 decks)

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