Sexual health Flashcards
CHLAMYDIA
What is the causative organism?
Chlamydia trichomatis
CHLAMYDIA
What are the symptoms is a female?
Asymptomatic
Increased vaginal discharge
Mucopurulent cervical discharge - yellow
Dysuria
PCB / IMB
Abdominal pain
Deep dyspareunia
CHLAMYDIA
What are the signs in a female patient?
Cervicitis
Cervical motion tenderness
Discharge
Abdominal pain
CHLAMYDIA
What are the symptoms in a male patient
Asymptomatic
Mucopurulent penile discharge
Dysuria / Urethritis
Testicular swelling
Pain on ejaculation
CHLAMYDIA
What are the signs in a male patient?
Abdominal tenderness
Epidiymo-orchitis
Reactive arthritis
CHLAMYDIA
What are the symptoms of rectal chlamydia
Asymptomatic
Anorectal discharge
Anorectal discomfort
CHLAMYDIA
What are the symptoms of oropharyngeal infection
Pharyngitis
Sore throat
CHLAMYDIA
How do you diagnose chlamydia in females
1st line: Vulvovaginal or endocervical swab - NAAT
2nd line: 1st catch urine
CHLAMYDIA
How do you diagnose chlamydia in males?
1st line: 1st catch urine
2nd line: Charcoal urethral swab for NAAT
*MSM - Anorectal and pharyngeal swabs
CHLAMYDIA
What extra test should be included for MSM patients with suspected chlamydia
Rectal swab - LGV
CHLAMYDIA
What is the manageemnt of chlamydia?
Doxycycline - 100mg BD 7 days
Erythromycin - If pregnant
CHLAMYDIA
Name 4 complications of chlamydia in women
PID
Infertility
Ectopic pregnancy
Conjunctivitis
Chronic pelvic pain
CHLAMYDIA
Name 4 complications of chlamydia in pregnancy?
Neonatal conjunctivitis
PROM
Low birth weight
Postpartum endometritis
CHLAMYDIA
What are the differentials for Chlamydia?
Mycoplasma genitalium
Lymphogranuloma venereum
CHLAMYDIA
What is Mycoplasma genitalium
Organism that causes a non-gonococcal urethritis
CHLAMYDIA
How do you diangose Mycoplasma genitalium
NAAT testing
Men - 1st pass urine
Female - Endocervical swab
CHLAMYDIA
What is required for a patient that has tested positive for mycoplasma genitalium
Tets for cure
Test for macrolide resistance
CHLAMYDIA
What is the treatment of mycoplasma genitalium
Doxycycline
Azithromycin
CHLAMYDIA
What is LGV
Lymphogranuloma venereum - common in MSM
CHLAMYDIA
Describe the stage of LGV
Primary - Painless ulcer
Secondary - Painful inguinal lymphadenitis
Tertiary - Proctitis / Tenesmus / Change in bowel habits
GONORRHOEA
What is the causative orgnaism
Neisseria gonorrhea
GONORRHOEA
How does gonorrhea present in females
Odourless purulent discharge
Dysuria
Pelvic pain
IMB
Dyspareunia
GONORRHOEA
What are the signs of gonorrhoea in a female patient
Discharge
GONORRHOEA
How does gonorrhoea present in a male patient?
Odourless purulent discharge
Dysuria
Testicular pain / swelling
GONORRHOEA
How do rectal and pharyngeal gonorrhoea infection present?
Usually asymptomatic
Anal - rectal discomfort
Pharyngeal - sore throat
GONORRHOEA
How do you diagnose gonorrhoea in women and men
Women
- vulvovaginal swab
- charcoal endocervical swab for MC&S
Men
- 1st pass urine
GONORRHOEA
What is the management of gonorrhoea
IM 1g Ceftriaxone - If sensitivities are unknown
Oral ciprofloxacin - If sensitivities known
GONORRHOEA
Describe the test for cure for gonorrhoea
Asymptomatic - NAAT
- 7 days after tx for RNA NAAT
- 14 days after treatment for DNA NAAT
Symptomatic - cultures
- 72 hours after treatment
GONORRHOEA
Name 5 complications associated with gonorrhoea
PID
Infertility
Conjunctivitis
Disseminated gonococcal infection
Septic arthritis
Endocarditis
Epidiymo-orchitis
Prostatitis
GONORRHOEA
What is disseminated gonococcal infection
complication of untreated gonococcal infection - bacteria spreads to skin and joints
non-specific skin lesions - dermatitis
Polyarthralgia
Migratory polyarthritis
Tenosynovitis
Systemic symptoms - fever and fatigue
SYPHILIS
What is the causative organism
Treponema pallidum
SYPHILIS
How can syphilis be transmitted
Oral / vaginal / anal sex
Vertical transmission
IVDU
Blood transfusions
SYPHILIS
Describe the primary stage
Painless chancre
Painless lymphadenopathy
SYPHILIS
Describe the secondary stage
Maculopapular rash - palms and soles of feet
Low grade fever
Lymphadenopathy
Oral lesions
Alopecia
Condylomata lata
SYPHILIS
Describe the tertiary stage
Gummatous lesions - granulomatous lesions with necrotic centre affecting skin, organs and bones
Aortic aneurysms
Aortic regurgitation
Neurosyphilis
SYPHILIS
Describe neurosyphilis
Headache
Dementia
Paralysis
Sensory impairment
Tabes dorsalis - demyelination of posterior columns of spinal cord
Argyll Robertson pupil
SYPHILIS
Describe the Argyll-Robertson pupil
Constricted pupil that accommodates when focussing on a near object but does not react to light
Irregular shape
SYPHILIS
What is latent syphilis
Occurs after secodnary syphillis - patient is asymptomatic despite still being infected
SYPHILIS
What is the difference between early latent and late latent syphilis
Early latent - within 2 years of initial infection
Late latent - from 2 years after initial infection
SYPHILIS
Describe the testing required for syphilis
Syphilis serology
Non-treponemal tests: Not sepcific for syphilis so high rate of FP
Rapid plasma reagin - PRP
VDRL
Assess the quantity of antibodies being produced
Negative following treatment
Treponemal specific tests: Specific for syphilis
TP-IEA
TPHA
Qualitative only
SYPHILIS
What are the causes of false positivies in non treponemal tests - cardiolipin
Pregnancy
SLE
TB
Malaria
HIV
SYPHILIS
What is the management of syphilis
Single dose of IM Benpen
TRICHOMONAS
What is the causative organism
Trichomonas vaginalis
TRICHOMONAS
What can trichomonas increase the chances of
Contracting HIV - Damaging vaginal mucosa
Bacterial vaginosis
Cervical cancer
PID
TRICHOMONAS
How does trichomonas present
Vaginal discharge - frothy green
Ithcing
Dysuria
Dysparerunia
TRICHOMONAS
What signs are present in a patient with trichomonas
strawberry cervix
vaginal pH > 4.5
TRICHOMONAS
How is trichomonas diangosed
women
- Charcoal swab with microscopy of posterior fornix or self taken vulvovaginal swab
wet mount - mobile trophitizes
men
- 1st catch urine
BACTERIAL VAGINOSIS
What is the causative orgaism
Gardenella vaginalis
BACTERIAL VAGINOSIS
What is BV
Overgrowth fo anaerobic bacteria and Loss of lactobacilli
Increase risk of developing an STI
BACTERIAL VAGINOSIS
Name 5 risk factors for BV
Multiple sexual partners
douching
recent antibiotics
smoking
copper coil
BACTERIAL VAGINOSIS
How does bacterial vaginosis present
Watery grey discharge - fishy smelling
Asymptomatic
BACTERIAL VAGINOSIS
What are not typical features of BV
Pain
Itching
Irritation
BACTERIAL VAGINOSIS
How doy you diangose BV
pH > 4.5
Charcoal swab
- High vaginal or vulvovaginal
Clue cells - microscopy
BACTERIAL VAGINOSIS
What are the risks of BV infection in pregnancy
Miscarriage
Preterm delivery
PROM
Chorioamnionitis
Low birth weight
Post partum endometritis
HERPES
Where does the virus lay dormant in the sensory nerve ganglia
HSV1 - Trigeminal nerve ganglion
HSV2 - Sacral nerve ganglia
HERPES
How does genital herpes present
Painful ulcers
Painful lymphaednopathy
neuropathic pain
dysuria
flu like sx
HERPES
How is it diangosed
clincal diagnosis
Viral PCR - can e taken
PELVIC INFLAMMATORY DISEASE
Name 3 causative rognaisms
Chlamydia trichomatis
Neisseria gonorrhoea
Mycoplasma genitalium
Gardenella vaginalis
PELVIC INFLAMMATORY DISEASE
Name 4 risk factors for PID
Not using barrier contraception
multiple sexual partners
younger age
existing STI
IUD
Previous PID
PELVIC INFLAMMATORY DISEASE
Describe the symptoms of PID
Lower abdominal pain
abnormal vaginal discharge
dysparerunia
fever
dysuria
IMB / PCB
PELVIC INFLAMMATORY DISEASE
Describe the signs of PID
Pelvic tenderness
Cervical motion tenderness
Cervicitis
Purulent discharge
PELVIC INFLAMMATORY DISEASE
How do you diagnose PID
Pregnancy test - exclude ectopic
NAAT - Chlamydia and gonorrhoea
NAAT - Mycoplasma
HIV test
Syphilis test
High vaginal swab
Bloods - CRP
PELVIC INFLAMMATORY DISEASE
What is the management of PID
IM Ceftriaxone - Gonorrhoea
Doxycycline - Chlamydia
Metronidazole - Gardenella
PELVIC INFLAMMATORY DISEASE
What are the complications of PID
Sepsis
Abscess
Infertility
Ectopic pregnancy
PELVIC INFLAMMATORY DISEASE
What is Fitz-Hugh-Curtis syndrome
Inflammation and infection of the liver capsule (Glisson’s capsule), leading to adhesions between the liver and peritoneum.
Bacteria may spread from the pelvis via the peritoneal cavity, lymphatic system or blood.
HIV
Name 4 AIDS defining illnesses
Kaposi’s sarcoma
Pneumocystitis jirovecii penumonia
CMV infection
Candidiasis - oesphoageal or bronchial
Lymphoma
TB
HIV
What is given prophylactically to patients with a low CD4 count
Co-trimoxazole - protect against pneumocystosis pneumonia
HIV
What shoudl HIV patients avoid
live vaccines
SEXUAL HEALTH
Describe triple swabs
Endocervical NAAT - CT
Endocervical charcoal swab - NG
HVS - CHarcoal for bacterial and fungal infections
CANDIDIASIS
Describe the presentation
Cottage cheese discharge
Pruritus
Erythema
Swelling
Superficial dysparerunia
SEXUAL HEALTH
Which sexual health conditions increase vaginal pH
BV
TV
SEXUAL HEALTH
Which sexual health conditions decrease vaginal pH
Candidiasis