Respiratory Flashcards
Give 4 sx of COPD
Productive cough
SOB
Wheeze
recurrent infections
How is SOB measured in COPD
MRC Dyspnoea scale
Signs of COPD
Use of accessory muscles
asterixis
Pursed lip breathing
Tachypnoea
Hyperinflation - barrel chest
decreased cricosternal distance
reduced chest expansion
hyperesonant - percussion
decreased breath sounds
wheeze
How does smoking cause COPD
Stimulates neutrophil elastase leading to destruction
Ix COPD
CXR
FBC
ABG
ECG
Spirometry
CXR findings in COPD
Hyperinflation
bullae
flat hemidiaphragm
Conservative management of COPD
Smoking cessation
pulmonary rehab
vaccination
signs of asthma
tachypnoea
chest hyperexpansion
hyper resonant
wheeze - polyphonic
Harrisons sulci
Investigations for asthma
Spirometry with BDR
FeNO >40ppb - eosinophilic airway inflammation
Peak flow variability >20%
Asthma triggers
Animals
infection
meds
cold weather
dust / mould
emotions
conservative asthma management
Education
smoking cessation
annual r/v
decrease weight
annual influenza
decrease exposure to triggers
sx of asthma exacerbation
worsening SOB
Use of accessory muscles
worsenign wheeze
tachpnoea
reduced air entry
investigations for asthma exacerbation
Bloods - FBC / CRP
PEFR
ABG - T2RF
CXR
Signs of life threatneing asthma exacerbation
33 92
Cyanosis
Hypotension
Exhaustion
Silent chest
Tachycardia
requirements for hospital discharge following exacerbation
PEF > 75% Predicted
inhaler technique checked
stable on meds for 12-24 hours
community management of asthma - adult
4 puffs
2 puffs every 2 mins
max 10 puffs
rpt every 20 mins
community management of asthma exacerbation - child
1 puff every 30-60s
max 10 puffs
Bronchiectasis causes
pneumonia
CF
Idiopathic
TB
Lung cancer
Bronchiectasis features
Productive cough
Sputum
dyspnoea
haemoptysis
clubbing
coarse inspiratory crackles
wheeze
Investigations for bronchiectasis
CXR - Thickened bronchial walls
Sputum culture + bloods
Spirometry - obstructive
High resolution CT - Diagnostic
Dilated airway and signet rings
Bronchiectasis management
smoking cessation
physiotherapy
education
Abx - azithromycin
Bronchodilators - wheeze / sob
RF for lung cancer
smoking
silica
coal
asbestos
radiation
HIV
Features of lung cancer
cough
SOB
Haemotysis
hoarse voice
fever
Squamous cell carcinoma paraneoplastic syndrome
PTH-rp –> Hypercalcaemia
2ww referral criteria for lung cancer
CXR suspicious findings
> 40 + unexplained haemoptysis
Causative organisms for CAP
Step penumoniae
H influenzae
Moraxella catrhalis
causative organisms for a HAP
Psudomonas aeruginosa
Staph aureus
Features of mycoplasma penumonia
cold AIHA
Erythema multiforme
Features of legionella pneumophilia
SIADH - low sodium
Lymphocytes
Features of penumocystisis jivorecci
HIV
Excercise induced dyspnoea
Dry cough
causative organisms of aspiration pneumonia
strep penumoniae
H influenzae
RF for aspiration penumoniae
stroke
MG
Alcoholics
post-ictal
mechnaical intubation
features of pneumoniae
productive cough
pleuretic chest pain
haemoptysis
fever
dyspnoea
classification of pneumothorax
spontaneous
- primary: young tall thin men
- secondary:
Asthma
COPD
TB
Penuminae
Lung cancer
Traumatic
what is sarcoidosis
multisystem disease characterised by inflammation and granuloma formation
What is the classical presentation / syndrome of sarcoidosis
Lofgrens syndrome
- erythema nodosum
- BHL
- Polyarthralgia
Features of sarcoidosis
- lungs
- heart
- liver
- kidneys
- PNS / CNS
- Eyes
- Derm
BHL
Pulmonary fibrosis
BBB/HB
Cirrhosis / cholestasis
Renal stones
Bells palsy
Diabetes insipidus
Uveitis
Lupus pernio
causes of BHL
Sarcoidosis
TB
Lymphoma
bronchial carcinoma
haemoptysis differentials
PE
Cancer
TB
Pneumoniae
Bronchiectasis
Goodpastures
Investigations for sarcoidosis
Bloods - FBC / U+E / CRP / ACE / Ca2+
Urien dipstick
ECG / Spirometry
CXR
Bronchoscopy + biopsy + histology
histological finding of sarcoidosis
Non caseating granuloma with epithelioid cells
Clincial features of sarcoidosis
fever
weight loss
SOB
Dry cough
What is TB
Chronic granulomatous disease caused by mycobacterium TB
Causes of re-activation of TB in latent disease
Immunosuppresion - steroids
Immunodeficiency
HIV / AIDS
DM
CKD
Lymphoma
Who is the BCG vaccine offered to
Neonates born in areas of the UK with high rates of TB
Neonates with relatives from countries with a high rate of TB
Neonates with a family history of TB
close contact with TB
Unvaccinated children or young adults that recently arrived from a country with a high rate of TB
Healthcare workers
features of TB
WEIGHT LOSS
fever
haemoptysis
cough
dyspnoea
night sweats
lymphadenopathy
TB investigations
Sputum sample and culture - 3 samples
Blood and blood cultures
CXR
Specialist tests for TB
Mantoux test
Inteferon gamma release assay
Causes of exudative PE
PE / Pneumoniae
Inflamm - SLE / R.A
Neoplasm
TB
Causes of transudative PE
HF
Liver cirrhosis
nephrotic syndrome
CKD
Hypoalbuminaemia
Hypothyroid
Meigs syndrome
features of PE
SOB
Pleuretic CP
Reduced exercise tolerance
signs of Pleural effusion
tachypnoeic
tahcycradic
tracheal deviation
decreased chest exapnsion
stoney dull percussion
reduced breath sounds
reduced TVF
Investigations for Pleural effusion
Bloods
- FBC / U+E / LFT - albumin / AST/ALT
CXR
Pleural aspiration and fluid analysis
what is measured in a pleural aspirate
LDH
Protein
pH
Gram stain
MC&S
Glucose
WCC
Outline the lights criteria
fluid : serum protein >0.5
fluid : serum LDH > 0.6
Pleural fluid LDH >2/3 upper limit of normal for serum
when do you suspect an empeyema
improving penumonia but ongoing fever
causes of interstitial fibrosis
coal / dust / silica
IPF
Medications
lung damage - penumonia / TB
alpha 1 antitrypsin
R.A
SLE
Sjogrens syndrome
Medications causing pulmonary fibrosis
amiodarone
MXT
Nitrofuranotin
features of pulmonary fibrosis
dry cough
SOB
Fatigue
clubbing
CT chnages of IPF
Ground glass
Reticualr opacities
Management of IPF
Smoking cessation
Pulmonary rehab
Physio
Advanced care plan
O2 therapy
Pirfenidone
Lung transplant
consequences of asbestos exposure
fibrinogenic
- lung fibrosis - lower lobes
- pleural plaques
carcinogenic
- adenocarcinoma
- mesothelioma
causes of hypersenitivity pneumonitis
farmers lung
mushroom workers lung
malt workers lung
bird fanciers lung