Sexual and Reproductive Health Flashcards

1
Q

what does serovars A-c chalymidia cause?

A

trachoma (eye infection = not an STI)

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2
Q

what does serovars D-K cause?

A

genital infectoin

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3
Q

what does serovars L1-L3 cause?

A

Lymphogranuloma venereum

MSM, can present as proctitis (blood OR tenesmus, pain), and can look like Chrohn’s, therefore test if risk of STI

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4
Q

what can be caused by women passing on chlamydia to their children at birth?

A

opthalmia neonaorum or chlamydia pneumonitis

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5
Q

what is the incubation period for chlamydia?

A

3-21 days

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6
Q

when should asymptomatic patients be tested for chalmydia?

A

14 days following exposure

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7
Q

what is the first line and alternative treatment for chlamydia?

A
  1. doxycycline 100mg BD x 1 week

2. azithromycin 1G on day 1, 500mg day 2 and 3

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8
Q

what is gonorrohea caused by and what is it seen as under the microscope?

A

gram-negatice intracellular diplococcus (seen a two kidney beans facing each other) called Neisseria Gonorrhoea

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9
Q

what is the treatment and dosage for Gonorrhoea?

A

ceftriaxone IM 1g stat

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10
Q

what are the symtptoms of trichomonas vaginalis

A

vaginal discharge: offensive, yellow/green, frothy
vulvovaginitis: itch/discomfort
strawberry cervic (microhaemorrages)
vaginal pH >4.5

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11
Q

how to treat trichomonas vaginalis?

A

oral metronidazole for 5-7 days

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12
Q

what is the average incubation time for HPV?

A

3 weeks - 9 months

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13
Q

what are the 3 types of different treatment options for HPV?

A

ablative - cryotherapy
topical - trichloroacetic acid, podophyllotoxin, imiquimod
surgical - diathermy, curretage, surgical excision

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14
Q

describe the primary infection of syphillis

A

up to 3 months
presents with painless chancre (ulcer) at site of inoculation and non-tender lymphadneopathy (unlike herpes simplex which is painful)

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15
Q

describe the secondary infection of syphilis?

A

up to 2 years
spreads across hte body
skin lesions and lesions on mucous membrnaes, pharyngitis, patchy alopecia, generalised lymphadenopathy, condylomata lata - infectious lesion secreting the bacteria
neurological and opthalamic involvement not uncommon

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16
Q

describe the latent stage of syphilis?

A

no symptoms but low level multiplication of spirochete in intima of small blood vessles
can be divided into early and latent periods

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17
Q

describe late stage syphilis?

A

cardiovascular, gummatous or neurovascualr complications many years later

18
Q

how do you diagnose syphilis?

A

PCR swab of 1 year and 2 year lesions, dark field microscopy

19
Q

how do you screen for syphilis?

A

EILSA / EIA for IgG / IgM antibodies (antibodies remain for life)

20
Q

if screening for syphilis is positive, what further tests are done?

A

treponema pallidum particle agglutination (TPPA) - specific for syphilis, remains positive lifelong but not helpful in monitoring

21
Q

how do you treat primary / secondary and early latent syphilis?

A

2.4MI benzathenepenicillin IM

22
Q

when are all pregnant woman offered syphilis screening?

A

8-12 week s

23
Q

describe genital herpes?

A

an enveloped virus containing double-stranded DNA

24
Q

what are the main symptoms of genital herpes?

A

blistering ulcers at external genitalia, pain, external dysuria, vaginal or urethrall discharge, local lymphadenopathy, fever and myalgia

25
describe how herpes invades the body
- virus replicates in dermis and epidermis, getting into nerve endings of senosry and autonomic nerves - inflammation at nerve endings = painful multiple small vesicles which are easily deroofed - virus migrates to sacral root ganglion and hides from immune system - virus can reactivate from there causing recurrent genital herpes
26
what is the incubation period of herpes?
3-6 days
27
what is the treatment of herpes?
oral aciclovir 400mg TDS x 5/7
28
what are some risk factors for candidia infection?
- recent AB therapy - high oestrogen levels (pregnancy, contraception) - poorly controlled DM - immunocompromised patients with CD4 counts below 100
29
how to diagnose candida?
high vaginal swab for culture
30
how to treat candida infection?
vaginal infeciton - fluconazole 150mg stat or clotrimazole 500mg pessary stat - topical cream (without hydrocortisone) can be used for external symptoms
31
what is the typical visible symptom of candida balanitis?
spotty rash
32
what is prostatitis usually caused by and why do all suspicions get an STI check?
E.coli sometimes by gonorrhoea or chlamydia anyone < 35 should get an STI check
33
what are the symptoms of prostatitis?
UTI symptoms | lower abdo pain / back / perineal / penile pain
34
how is prostatitis tested for?
MSSU (middle stream) urine sample | +- first pass urniary sample
35
how to treat prostatitis?
ofloxacin 400mg bd for 28 days
36
what vaginal pH Is seen in BV?
>4.5
37
what will be seen in a wet mount sample from a vagina with BV?
clue cells - the absence of bacilli and their replacement with clumps of coccobacilli also leads to this diagnosis
38
how to treat BV?
oral mentronidazole for 5 days
39
how does HIV attach to the CD4 molecule?
via a protien called gp120
40
when may patients with HIV start to get symptoms?
CD4 <200 cells / mm3 | patients will start to get opportunistic infections eg pnuemocystitis pneumonia
41
what are some examples of AIDS-defining conditions?
- recurrent bacterial pneumonia - pneumocystis pneumonia - fungal infections - candidiasis of the oesophagus - Kaposi's sarcoma