Sex Chromosomes & Sex Linkage Flashcards

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1
Q

not every organism has ____

A

sex chromosomes or even separate sexes

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2
Q

monoecious

A

in many plants and animals, every individual is both male and female

1 individual makes both male and female gametes

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3
Q

dioecious

A

organisms where there are separate males and females

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4
Q

all vertebrates are …

A

dioecious

in lower vertebrates however, males and females are not high differentiated

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5
Q

if sexes are not highly differentiated, then

A

there may be no special sex chromosomes

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6
Q

species with highly differentiated sexes also have differentiated _____

A

sex chromosomes

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7
Q

sex in humans is typical of …

A

placental mammals, in its biology, genetics, and cytogenetics

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8
Q

XX makes

A

females

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9
Q

XY makes

A

males

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10
Q

nonsex chromosomes are called

A

autosomes

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11
Q

humans have __ pairs of autosomes and __ pair of

A

autosomes, sex chromosomes (either XX or XY)

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12
Q

the X is …

A

big and metacentric

centromere near the middle

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13
Q

the Y is …

A

small and acrocentric

centromere very close to the end

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14
Q

X and Y act as a …

A

pair of homologs

even though they look different

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15
Q

what happens to X and Y in meiosis?

A

form a bivalent but only at the tips

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16
Q

psuedo-autosomal regions

A

Y pairs with X only in these regions on the tips

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17
Q

non-recombining region

A

male-specific region

located between the tips of the Y chromosome

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18
Q

do X chromosomes in the female recombine with each other?

A

yes, just like a normal pair of autosomes

they make a “normal” bivalent where recombination can happen anywhere along the length

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19
Q

chromosomal sex determination ensures..

A

equal numbers of males and females

20
Q

SRY gene

A

found only on the Y chromosome on the short arm

near the end of the non-recombining region of Y

responsible for initiating male development

21
Q

TDF

A

testis-determining factor

22
Q

SRY makes

A

TDF protein

23
Q

in the presence of TDF….

A

the testis-determining facror turns gonads into testes instead of ovaries

24
Q

is SRY a dominant gene?

A

yes, only one copy makes you male

25
Q

is SRY a pleitropic gene?

A

yes, it has multiple effects

26
Q

testes make…

A

testosterone and other androgens

all are male sec hormones

27
Q

male sec hormones cause…

A

the body’s organs to develop male characteristics

28
Q

androgen insensitivity syndrome

A

AIS

no receptors for androgens

29
Q

sex-limited traits

A

secondary sex characteristics

30
Q

sex-limited traits include all…

A

of the typical physical differences between men and women

31
Q

sec limited traits can be produced…

A

in either sex, just by male or female hormones acting during development

32
Q

the signal for sex-limited traits to develop comes from…

A

steroid hormone balances

33
Q

the genes that control the growth of sex-limited traits are …

A

distributed all over the chromosomes

34
Q

sex-linked traits are caused…

A

by genes of the sex chromosomes

35
Q

genes on the X chromosome

A

more than 1000

random set of genes for varied functions

similar to a typical autosome

36
Q

the human Y has…

A

150-200 transcription units (majority not protein-coding)

codes for 30 different proteins

11 function in the testes (all in male-specific region)

37
Q

hemizygous

A

situations where a diploid has only one allele for a gene

due to a deletion of one homolog, for example

38
Q

males are hemizygous for …

A

most of the genes of the X chromosome

they only have 1 copy

39
Q

exceptions to hemizygous males

A

small number of genes in psudo-autosomal regions have 2 copies

40
Q

males get …

A

all the recessive genetic disorders on the X is they inherit only one recessive allele

41
Q

sex linked genetic disorders

A

about 100 X-linked diseases

most are recessive due to alleles on X-chromosome genes

almost all occur in males

42
Q

males can only get an X from…

A

their mothers

43
Q

males can only pass an X to their…

A

daughters

44
Q

sons cannot get an x-linked disease from…

A

their fathers

45
Q

sons can only get an x-linked disease from…

A

their mothers