Session 7 ILO's - Genotype, Phenotype, Inheritance

Question 1

Clearly define genotype and phenotype

Question 2

Clearly define gene and allele

Question 3

Be confident using general inheritance terminology

Question 4

Draw a family pedigree according to convention from a given family history

Question 5

Relate genetic information from a pedigree and describe the family concerned

Question 6

Use genetic data to calculate probability of inheritance and recombination frequency

Question 7

Explain and describe Mendelian autosomal and sex-linked inheritance patterns

Question 8

Describe mitochondrial inheritance

Question 9

Explain and describe in general terms polygenic and multifactorial inheritance

Question 10

Understand how are genotypes translated into phenotypes

Question 11

Explain the factors that influence how genotypes are translated into phenotypes

Question 12

Explain different modes of inheritance: dominant, recessive; autosomal, sex-linked

Question 13

Understand pedigree analysis, how to draw a pedigree tree and how to calculate the probability of suffering from a disease

Question 14

Explain polygenic traits, penetrance and expressivity

Question 15

Understand polygenic traits, and the meaning of linkage, penetrance and expressivity