Serum biomarkers in ovarian GERM CELL tumors Flashcards
Dysgerminoma
Beta-hCG
LDH
“Distant Germans betta have long distance”
Endodermal sinus tumor (yolk sac)
AFP
Egg yolk can only be awesome fresh picks (AFP) if you keep them in chiller (Schiller Duvall Bodies)
Choriocarcinoma
Beta-hCG
Immature teratoma
AFP
LDH
CA 125
Immature ladies are from Pasadena (AFP) California
Embryonal carcinoma
Beta-hCG
AFP
Embryo are betta as fresh picks (AFP)
Squamous components = most likely to become malignant while
Neural components = used to GRADE the immature teratoma
Benign cystic tumors
Increased LDH (sensitive to irradiation)
Dysgerminoma
Increased hCG
Choriocarinoma
Increased AFP, Schiller Duvall bodies (rapid growth)
Endodermal sinus tumor
Increased hCG, AFP
Embryonal
Rare
Polyemberyoma
Malign at only if there are associated dysgerminoma elements
Gonadoblastoma