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Gyn-Onc/Surgery > Ovarian Cancer Facts > Flashcards

Ovarian Cancer Facts Flashcards

1
Q

Covers 80-85% of all ovarian tumors; age at diagnosis usually older than 40 years

A

Coelemic epithelial

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2
Q

Tumors includes in coelemic epithelial tumors

A

Serous, mucinous, endometrioid, clear cell, brenner

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3
Q

Histogenesis of serous tumors

A

Ciliated tubal epithelium

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4
Q

Histogenesis of mucinous tumors

A

Columnar endocervical epithelium

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5
Q

Histogenesis of endometrioid tumors

A

Endometrial glands

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6
Q

Histogenesis of clear cell tumors

A

Mesonephric tissue

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7
Q

Histogenesis of brenner tumor

A

Transitional urothelium

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8
Q

What are the unique findings of serous tumors and what is the tumor marker?

A

Psamomma bodies

Tumor marker = CA -125

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9
Q

What are the unique findings of mucinous tumors

A

Pseudomyoxoma peritonei

Tumor marker = CEA

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10
Q

What is the tumor marker for endometrioid tumor?

A

CA-125

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11
Q

What is the tumor marker for clear cell tumors?

A

CA-125

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12
Q

What is the unique findings for brenner tumors?

A

Walthard cell rests

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13
Q

What is the percent malignancy of serous tumors?

A

20%

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14
Q

What is the percent malignancy of mucinous tumors?

A

15%

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15
Q

What is the percent malignancy of Endometrioid tumors?

A

95%

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16
Q

What is the percent malignancy of Clear cell tumors?

A

98%

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17
Q

What is the percent malignancy of Brenner tumor?

A

2%

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18
Q

Covers 10-15% of all ovarian tumors; age at diagnosis is usually younger than 30y/o

A

Germ cell tumor

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19
Q

Tumors included in germ cell tumors

A

Teratoma (immature and mature)

Dysgerminoma

Gonadoblastma

Endodermal sinus (“yolk sac tumor”)

Embryonal carcinoma

Non-gestational choriocarcinoma

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20
Q

Histogenesis of immature teratoma

A

Fetal embryonic tissue

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21
Q

Histogenesis of mature teratoma

A

Many mature cell types

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22
Q

Histogenesis of dysgerminoma

A

Primitive germ cells

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23
Q

Histogenesis of dysgerminoma

A

Primitive germ cells

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24
Q

Histogenesis of gonadoblastoma

A

Dysgenetic gonads with Y chromosomes

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25
Q

Histogenesis of endodermal sinus (“yolk sac tumor”)

A

Extraembyonic tissue

26
Q

Histogenesis of embryonal carcinoma

A

Embryonic tissue

27
Q

Histogenesis of non-gestational choriocarcinoma

A

Extraembryonic tissue

28
Q

Tumor markers of immature teratoma

A

AFP and CA-125

29
Q

Unique findings of Mature teratoma

A

Rokitansky prominence

30
Q

Tumor marker for dysgerminoma

A

LDH

31
Q

Unique findings of endodermal sinus “yolk sac tumor”

A

Schiller Duvall bodies

32
Q

Tumor markers of embryonal carcinoma

A

AFP

Beta-hCG

33
Q

Tumor markers of endodermal sinus “yolk sac tumor”

A

AFP

34
Q

Tumor markers of non-gestational choriocarcinoma

A

Beta-hCG

35
Q

% malignant of immature teratoma

A

100%

36
Q

% malignant of mature teratoma

A

0-1%

37
Q

% malignant of Dysgerminoma

A

100%

38
Q

% malignant of Gonadoblastoma

A

0%

39
Q

% malignant of Endodermal sinus “yolk sac tumor”

A

100%

40
Q

% malignant of Embryonal carcinoma

A

100%

41
Q

% malignant of Non-gestational choriocarinoma

A

100%

42
Q

Covers 3-5% of all ovarian tumors; age at diagnosis is usually around 50yrs with a range of 20-80

A

Gonado-stromal

43
Q

Histogenesis of granulosa cell tumors

A

Ovarian gonadal cells

44
Q

Histogenesis of fibroma

A

Thecoma elements

45
Q

Histogenesis of thecoma

A

Thecoma elements

46
Q

Histogenesis of steroli-leydig tumor

A

Testicular gonadal cells

47
Q

Histogenesis of lipid cell tumor

A

Gonadal stromatolites cells

48
Q

Histogenesis of gynandroblastoma

A

Both ovarian and testicular cells

49
Q

Unique findings of granulosa cell tumors

A

Cal-Exner bodies

Estrogen production

Inhibin

50
Q

Unique findings of Fibroma

A

Seen w Meig’s syndrome

51
Q

Unique findings of Thecoma

A

Estrogen production

52
Q

Unique findings of Serotonin-leydig

A

Crystals of Reinke

Testosterone production

52
Q

Unique findings of Serotonin-leydig

A

Crystals of Reinke

Testosterone production

53
Q

Unique findings of Gynandroblastoma

A

Testosterone production

54
Q

% malignancy of granulosa cell tumor

A

<5%

55
Q

% malignancy of Fibroma

A

<5%

56
Q

% malignancy of Thecoma tumor

A

<5%

57
Q

% malignancy of Seroti-leydig tumor

A

<5%

58
Q

% malignancy of Lipid cell

A

30%

59
Q

% malignancy of Gynandroblastoma

A

100%

Gyn-Onc/Surgery (11 decks)

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