Seronegative spondyloarthropathies Flashcards
The ‘seronegative spondyloarthropathies’ are associated with which gene?
Which conditions are included in this group?
HLA-B27
- Ankylosing spondylitis
- Reactive arthritis
- Psoriatic arthritis
Which locations are most commonly affected by ankylosing spondylitis?
Vertebral column
Sacroiliac joints
What are the typical XR findings associated with ankylosing spondylitis?
“Bamboo spine” + 4 S’s:
- Subchondral erosions
- Sclerosis
- Squaring of lumbar vertebrae
- Sacroiliitis
The ‘typical’ patient with ankylosing spondylitis is a…
Young male
Describe the typical symptoms of ankylosing spondyltis
Lower back pain and stiffness which is worse with rest and improves with movement
Which symptom is important to ask about when considering ankylosing spondylitis as a differential?
Pain wakes them from sleep
Give an example of a key complication of ankylosing spondylitis
Vertebral factures
Reactive arthritis may also be called…
Reiter syndrome
The most common infections which trigger reactive arthritis are…
Gastroenteritis
STI
The classical triad of reactive arthritis can be remembered with the saying…
Cant’ see (anterior uveitis)
Can’t pee (balanitis)
Can’t climb a tree (arthritis)
Which signs may be present in the hands and nails in a patient with psoriatic arthritis?
- Pitting of the nails
- Onycholysis
- Dactylitis
The first-line drug management for all of the seronegative spondyloarthropathies is with…
NSAIDs
