Seronegative arthritis Flashcards
Does seronegative arthritis involve rheumatoid factor?
No
What are some characteristics of seronegative arthritis?
Usually asymmetric
Involves axial skeleton
Enthesitis
Some extra-articular features like uveitis and IBD
What are some common presentations of seronegative arthritis?
Reactive arthritis
Psoriatic arthritis
Bowel related arthritis (Crohn’s, UC)
Ankylosing spondylitis
Is ankylosing spondylitis more common in males or females?
Males
What is ankylosing spondylitis?
Chronic inflammatory rheumatic disorder usually affecting axial skeleton and entheses
What is the NY criteria used for?
Diagnosing ankylosing spondylitis
What are the NY criteria?
Inflammatory back pain
Limitation of movements in antero-posterior as well as lateral planes at lumbar spine
Limitation of chest expansion
Bilateral sacroiliitis on X-rays
How is spinal movement assessed?
Modified Schober’s test to assess lumbar flexion and lateral spinal flexion (Reaches down side of leg and marks point)
Measure angle of cervical rotation from midline
What are the main features of management of AS?
Physiotherapy
NSAIDs
Anti-TNF
Anti-IL-17
How would AS be managed surgically?
Joint replacement
Spinal surgery
What are some treatment options for psoriatic arthritis?
Sulfasalazine Methotrexate Leflunomide Cyclosporine Anti-TNF therapy Anti- IL-17 and IL-23 Steroids Physiotherapy and occupational therapy
What is reactive arthritis?
Sterile synovitis after distant infection including salmonella, shigella, yersinia, campylobacter, chlamydia, borrelia, neiserria, strep
What does Reiter’s arthritis involve?
Arthritis
Urethritis
Conjunctivitis
What is enteropathic arthritis commonly associated with?
IBD (Crohn’s or UC)
How is enteropathic arthritis treated?
NSAIDs difficult to use Sulfasalazine Methotrexate Leflunomide Cyclosporine Anti-TNF therapy Anti- IL-17 and IL-23 Steroids Physiotherapy and occupational therapy
