Serologic Markers for the Diagnosis of Hepatitis B Virus Infection Flashcards

1
Q

hepatitis B surface antigen, the envelope protein consisting of three polypeptides

A

HBsAg

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2
Q

antibody to hepatitis B surface antigen

A

Anti-HBs

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3
Q

antibody to hepatitis B core antigen

A

Anti-HBc

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4
Q

antigen associated with the nucleocapsid, also found as soluble protein in serum

A

HBeAg

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5
Q

antibody to hepatitis B e antigen

A

Anti-HBe

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6
Q

HBsAg indication (3)

A

★ Active HBV infection
★ long-term carrier (after 6 months of acute infection)
★ incubation period

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7
Q

IgM anti-HBc indication (3)

A

★ Appears early in the course of the disease
★ Acute infection
★ Confirms the diagnosis of acute HBV in cases where HBsAg is not detected and anti-HBs has not yet appeared

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8
Q

anti-HBs indication

A

Convalescence or immune status

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