Septic arthritis Flashcards

1
Q

Common cause of infection

A
  1. Perforating injury
  2. Intra-articular injection
  3. post-operative infection of joint/tissues
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2
Q

Common etiology traumatic infections

A

enteric bacteria

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3
Q

Common etiology of iatrogenic infections

A

Staphylococcus aureus

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4
Q

Septic arthritis

A
  1. Acute
  2. purulent exudate
  3. rapid destruction articular cartilage
    - lysosomal enzymes released by neutraphils
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5
Q

Modes of joint infections

A
  1. Primary: direct penetration
  2. Secondary: extension of infection from adjacent tissues into joint
  3. Tertiary: Hematogenous from other infected area
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6
Q

Young animals

A
  • 1 or more joints involved

- usually hematogenous

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7
Q

Older animal

A
  • Usually only 1 joint

- Usually from direct penetration or extension from adjacent infection

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8
Q

Clinical signs

A
  1. Extreme pain, ush not weightbearing
  2. Heat and swelling around infected joint
  3. Fluid distention and edema
  4. Foals may present with septicemia
  5. Septic arthritis may be discovered during foal exam
  6. Animal may be depressed, off feed, sweating, febrile
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9
Q

Classification of hematogenous septic arthritis/osteomyelitis in foals

A

S type: synovial
E type: epiphyseal - worst prognosis
P type: physeal

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10
Q

S type infection

A
  • Confined to joint space

- No evidence of osteomyelitis

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11
Q

E type

A
  • Infection begins in subchondral bone of epiphysis
  • May extend through articular cartilage into joint
  • Worst prognosis because of collapse of unsupported articular cartilage
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12
Q

P type

A

Infection begins near physis

-from metaphyseal side

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13
Q

Radiographic signs

A
  1. Early-soft tissue swelling, increase in joint space if limb weighbearing
  2. Late-narrowing of joint space, lysis subchondral bone, periosteal proliferation
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14
Q

Diagnosis

A
  1. PE
  2. CBC/CHem
    - adult horses: hyperfibrinogenemia, +/- high/normal WBC
    - Foal: moderate leukocytosis, neutrophilia, hyperfibrinogenemia, blood culture
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15
Q

Clin path joint fluid

A
  1. yellow/grey/blood tinged/cloudy/fibrin/pus
  2. 20,000-200,000 leukocytes/mm3; > 90% neuts
  3. Low pH (normal is 7.3)
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16
Q

Culture of joint

A
  1. Negative culture doesn’t rule out infection

2. Cetrifugation and culture of sediment

17
Q

Differentiate septic arthritis from

A

fractures

osteomyelitis

18
Q

Diagnosis septic arthritis is by

A

arthrocentesis

-don’t delay if you suspect septic joint

19
Q

Joint ill in foals check for

A
  1. Diarrhea
  2. Umbilical infection
  3. Pneumonia
  4. Systemic illness
  5. Infection in other joints
20
Q

Common enterobacteriacea

A
  1. E. Coli
  2. Enterobacter sp
  3. Klebsiella sp
  4. Proteus sp
  5. Providencia sp
  6. Salmonella sp
21
Q

Other common etiology

A
  1. Actinobacillus equuli
  2. Streptococcus sp
  3. Rhodococcus equi
22
Q

Treatment

A
  1. Joint lavage isotonic fluids-then instill abx in joint
  2. IV regional limb perfusion
  3. broad spectrum antibiotics
    - penicillin + aminoglycoside (gent)
    - rifampin + clarithromycin
    - enrofloxacin
  4. supportive bandages and cold therapy
  5. NSAIDS
  6. IV sodium hyaluronate or IM adequan during recup
23
Q

Regional limb perfusion

A

Use 1/3 the systemic dose
Tourniquet for 30 minutes
Can do intraosseous

24
Q

DMSO joint lavage

A
  1. 10-40% solutions
  2. Oxygen-derived free radical scavenger
  3. antibiotic properties
  4. not approved for this use
25
Q

Other pain management

A
  1. Epidural alpha 2s

2. fentanyl patch