Septic Arthritis

Question 1

Pathogen entry

Answer 1

Microorganisms enter the joint via -
Hematogenous spread,
Trauma, surgery, injections
Contagious

Question 2

Acute inflammatory response

Answer 2

Immune system responds-releasing inflammatory meditators like cytokines
Synovium thickens
Neutrophils and the pathogen release enzymes that degrade the cartilage

Question 3

Progressive joint damage

Answer 3

Inflammation destroys cartilage & subcondral bone further impairing blood flow contribute to necrosis

Question 4

Chronic stage

Answer 4

Chronic inflammation leads to joint fibrosis, potential ankylosing
Significant functional loss & deformity

Question 5

What is it?

Answer 5

Septic Arthritis is a joint infection caused by microbial invasion, leading to inflammation, cartilage destruction, and joint damage. It is a medical emergency requiring prompt diagnosis and treatment.