Septation of the heart and Congenital Defects

Question 1

What does the sinus venosus become?

Answer 1

-sinus venarum and coronary sinus

Question 2

What does the primitive atrium become?

Answer 2

R + L atrium

Question 3

What does the primitive ventricle become?

Answer 3

most of the definitive left ventricle

Question 4

Bulbus Cordis becomes

Answer 4

right ventricle and outflow tract

Question 5

Truncus Arteriosus become

Answer 5

ascending aorta and pulmonary artery [conotruncal septum]

Question 6

The right side of the primitive atrium becomes?

Answer 6

right atriums pectinate

Question 7

What is the crista terminalis?

Answer 7

-carry SA to AV node impulses

Question 8

What is SEPTA and VALVES?

Answer 8

s: divides R/L chambers

V: flow of blood

Question 9

How does the formation of septation occur?

Answer 9

-endocardial cushions (thickens up in the middle)

-Interatrial septum ( grows down)

-interventricular septum( grow up)

Question 10

What occurs on Day 28 ?

Answer 10

-septum primum and endocardial cushions appear

Question 11

what occurs in fetus heart on day 56?

Answer 11

-2nd septum and rapid growth of endo cardial tissues

Question 12

Foremen secundum is:

Answer 12

Before the foramen primum closes - the septum primum develops small perforations to form a new foramen

Question 13

Atrial Spetal Defect and the result:

Answer 13

-septum secundum is too short to cover foramen secundum

-results: right atrial and right ventricular hypertrophy may develop b/c PRESSURE is higher on LEFT atrium

Question 14

Atrial septal defect: (betsy terms)

Answer 14

O2 blood should go to ventricle but its going to the right side so RIGHT side enlarge

Question 15

Ventricular Septation:

Answer 15

occurs on 7th week and is NOT part of fetal circulation

-once closed, always closed

-grows cranially to allow blood to Ventr and bulbis cordis

Question 16

Ventricular Septation (DEFECT)

Answer 16

-superior part of the the interventricular foramen fails to form thus causes the mixing of blood btw the ventricles.

-left side has high pressure bc its stronger

Question 17

Truncus Arteriosus Septations from tissue from lateral wall flows out from:

Answer 17

truncus arteriosus and bulbus cordis

Question 18

The fusion and making of the septum called

Answer 18

-conotruncal septum which spiral at 180

-divides the aorta and pulmonary trunck in 2 differnt outflow tracts

Question 19

Tetralogy of Fallot (primary defect)

Answer 19

-UNEQUAL DIVISION of the outflow

Question 20

Tetralogy Fallot results in 4 consequences:

Answer 20

• pulmonary stenosis
• ventricular septal defect
  -displacement of aorta
  -right ventricular hypertrophy

(exhibit cyanotic skin while crying)

Question 21

Transposition of the Greater Arteries (TGA)

Answer 21

-conotruncal septa develop but does NOT SPIRAL into correct position

-left ventricle empties to pulmonary and right ventricle goes to aorta

has to have septal defect or PDA to survive

Question 22

Aortic arches dev’t: 3-6 becomes the

[Coarctation of the Aorta]

Answer 22

3: common carotids, internal/external carotids

4: also part of subclavian

6: pulmonary artery/ trunks, truncus arterious

Question 23

Ductus arteriosus is from the:

Answer 23

• 4th pharyngeal arch (left)

Question 24

Infantile Coarctation

Answer 24

defect in dev’t and regression of the 4th and 6th pharyngeal arch of arteries

Question 25

Formaen Ovale

Answer 25

The septum secundum forms lateral to the

Question 26

Formaen Ovale

Answer 26

The septum secundum forms lateral to the